PREDOMINANCE AND CLINICAL CHARACTERISTICS OF BURKITT LYMPHOMA IN SUDANESE PATIENTS
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2017, Vol 4, Issue 10
Abstract
Introduction: Burkitt lymphoma (BL) is a type of B lymphocyte lymphoma characterized with high proliferation rate. This study aimed to investigate age and gender distribution in addition to the predominant sites of cancer among Sudanese patients with BL. Materials and Methods: This was retrospective cross-sectional study conducted in private histopathology laboratory at Khartoum state-Sudan, during the period from June 2014 to June 2017. The data were collected from 35 confirmed BL patients’ file records at the histopathology laboratory. Archived Paraffin embedded sections were processed and prepared stained tissue slides re-interpreted by haematoxylin and Eosin in addition to the Immunohistochemistry panel for confirmation. Results: The study conducted on 35 BL patients (60% males, 40% females), with Male: Female ratio, 1.5:1, their age ranged between (2-57) years old. 54.29% of them their age were less than 5 years old and 14.29% were more than 18 years old, while 31.43% their aged ranged between 6-18 years. The collected samples showed that the Burkitt’s lymphoma found at mandibular, pelvic mass, tongue and abdominal lymph node site, usually at adult age group (above the 18 years old) and mainly found in a females group, while for children less than 18 years old, Burkitt’s lymphoma present mostly in male group at abdominal mass, abdominal lymph nodes, terminal lymph nodes and appendix. Conclusion: The study revealed that Sudanese children under 5 years old and younger people were more susceptible to the disease, commonly male patients and the most cancer site involved is the abdomen.
Authors and Affiliations
Abdel Rahim Mahmoud Muddathir
MORICANDIA ARVENSIS CHLOROFORM EXTRACT INCREASES T-LYMPHOCYTE PROLIFERATION, SUPPRESSES NO PRODUCTION, AND AFFECTS CELL ANTIOXIDANT ACTIVITY IN VITRO
Moricandia arvensis (Brassicaceae/crucifer) is a medicinal plant widespread in southern Tunisia. Despite its many uses in traditional medicine, there is no report addressing the effects of M.arvensis extracts on mice imm...
A REVIEW ON ANTICANCER POTENTIAL OF THIAZOLE-HETEROCYCLIC HYBRID COMPOUNDS
In anticancer drugs, hybrid structure are of great therapeutic interest due they can potentially overcome most of the pharmacokinetic drawbacks. Thiazole-heterocyclic hybrid derivatives are another class of heterocyclic...
PREVALENCE OF HEARING IMPAIRMENTS IN DIFFERENT AGE GROUPS OF ELURU, WEST GODAVARI DISTRICT, A.P.
Current human studies are indicating different hearing problems are common among general public. Hearing problems are projected to become among the top ten disabilities according to the WHO in the near future. Here we de...
CONTRIBUTION TO THE BIOTECHNOLOGICAL POTENTIAL STUDY OF ISOLATED LACTIC LEVAINS OF FERMENTED CASSAVA FOR THE PRODUCTION OF ADJOUKROU, AHIZI AND EBRIÉ ATTIÉKÉ
The current work aims to study the typology of the lactic starter isolated from the fermented cassava for the production of Adjoukrou, Ahizi and Ebrié attiéké. The objective is to highlight the contribution of autochthon...
ANTIBACTERIAL ACTIVITY OF DIFFERENT EXTRACT OF CURCUMA LONGA IN THE MANAGEMENT OF FISTULA IN ANO
Ayurvedic parasurgical treatment procedure Ksharasutra was one of the effective treatment for management of the fistula in ano. Curcuma longa was the one of the main ingredient in a thread. In the present work an attempt...