PREDOMINANCE AND CLINICAL CHARACTERISTICS OF BURKITT LYMPHOMA IN SUDANESE PATIENTS
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2017, Vol 4, Issue 10
Abstract
Introduction: Burkitt lymphoma (BL) is a type of B lymphocyte lymphoma characterized with high proliferation rate. This study aimed to investigate age and gender distribution in addition to the predominant sites of cancer among Sudanese patients with BL. Materials and Methods: This was retrospective cross-sectional study conducted in private histopathology laboratory at Khartoum state-Sudan, during the period from June 2014 to June 2017. The data were collected from 35 confirmed BL patients’ file records at the histopathology laboratory. Archived Paraffin embedded sections were processed and prepared stained tissue slides re-interpreted by haematoxylin and Eosin in addition to the Immunohistochemistry panel for confirmation. Results: The study conducted on 35 BL patients (60% males, 40% females), with Male: Female ratio, 1.5:1, their age ranged between (2-57) years old. 54.29% of them their age were less than 5 years old and 14.29% were more than 18 years old, while 31.43% their aged ranged between 6-18 years. The collected samples showed that the Burkitt’s lymphoma found at mandibular, pelvic mass, tongue and abdominal lymph node site, usually at adult age group (above the 18 years old) and mainly found in a females group, while for children less than 18 years old, Burkitt’s lymphoma present mostly in male group at abdominal mass, abdominal lymph nodes, terminal lymph nodes and appendix. Conclusion: The study revealed that Sudanese children under 5 years old and younger people were more susceptible to the disease, commonly male patients and the most cancer site involved is the abdomen.
Authors and Affiliations
Abdel Rahim Mahmoud Muddathir
Keywords
Related Articles
- EP ID EP629055
- DOI -
- Views 140
- Downloads 0
DEFIBROTIDE: A MAJOR BREAKTHROUGH TO FIGHT VENOOCCLUSIVE DISEASE (VOD) OF HEMATOPOIETIC STEM CELL TRANSPLANTATION
Venoocclusive disease (VOD) is a serious drawback of the standard Hematopoietic stem cell transplantation (HSCT) therapy. Day+ 100 survival of VOD patients after HSCT is very low (about 20%).[1] Previously the standard t...
UNUSUAL BILATERAL PROXIMAL ATTACHMENTS OF THE PECTORALIS MINOR MUSCLE: A CASE REPORT ON CADAVER DISSECTION
The pectoralis minor muscle is one of the muscles connecting the upper limb to the thoracic wall. It is a triangular muscle lying in deep relation to the pectoralis major. This is a case report on a possible variation in...
TRANSIENT ISCHEMIC ATTACK AS A PREDICTOR OF STROKE
Transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by focal brain or retinal ischemia, with clinical symptoms typically lasting less than one hour, and without evidence of acute infarct...
KNOWLEDGE AND PRESCRIBING PRACTICE OF PHYSICIANS TOWARD ANTIMICROBIAL RESISTANCE IN HEALTHCARE SETTING, DIYALA, IRAQ
Background: Antimicrobial resistance has increasingly become one of the most critical public health issue. The prescribing behavior of physicians plays a key role in controlling and reduction of antimicrobial resistance....
PREVALENCE OF HEARING IMPAIRMENTS IN DIFFERENT AGE GROUPS OF ELURU, WEST GODAVARI DISTRICT, A.P.
Current human studies are indicating different hearing problems are common among general public. Hearing problems are projected to become among the top ten disabilities according to the WHO in the near future. Here we de...