Preemptive Epidural Analgesia with Bupivacaine and Sufentanyl and the Effects of Epiduraly Added Epinephrine for Thoracic Surgery
Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2010, Vol 3, Issue 1
Abstract
Aim. The aim of the study was to determine if preemptive epidural analgesia in thoracic surgery reduces postoperative pain, and to compare these effects in relation to the usage of epinephrine. Material and Methods. Sixty patients admitted for thoracic surgery were randomly allocated into three groups (n = 20 each). Group A received bupivacaine and sufentanyl epiduraly prior to skin incision, followed by infusion of bupivacaine and sufentanyl. Group B (control) received saline in the epidural. In both groups patients received bupivacaine and sufentanyl epiduraly at the time of the chest closure. In Group C the same doses of bupivacaine and sufentanyl as in Group A were given to the patients including epinephrine in the epidural mixture. The level of statistical significance was pointed at p < 0.05. Results. The patients in Group A had lower intraoperative isofluran requirements, lower postoperative epidural infusion rates and lower pain scores in first eight postoperative hours, compared with the control. In the epinephrine group patients had lower pain intensity and smaller needs for postoperative epidural infusion rate than those in Group A. Conclusion. The usage of epinephrine has caused less nausea and easier mobilization. While there was a beneficial effect of the reduced intraoperative anesthetic requirements, any lasting effect of preemptive analgesia did not extend beyond eight hours after the operation.
Authors and Affiliations
Gordana Taleska| Clinic of Anesthesiology, Reanimation and Intensive Care, Faculty of Medicine, University “Ss Kiril and Metodij”, Skopje, Republic of Macedonia, Trajanka Trajkovska| Clinic of Anesthesiology, Reanimation and Intensive Care, Faculty of Medicine, University “Ss Kiril and Metodij”, Skopje, Republic of Macedonia, Anita Kokareva| Clinic of Anesthesiology, Reanimation and Intensive Care, Faculty of Medicine, University “Ss Kiril and Metodij”, Skopje, Republic of Macedonia, Anita Popovska| Clinic of Anesthesiology, Reanimation and Intensive Care, Faculty of Medicine, University “Ss Kiril and Metodij”, Skopje, Republic of Macedonia, Maja Naumoska| Clinic of Anesthesiology, Reanimation and Intensive Care, Faculty of Medicine, University “Ss Kiril and Metodij”, Skopje, Republic of Macedonia, Aleksandra Gavrilovska| Clinic of Anesthesiology, Reanimation and Intensive Care, Faculty of Medicine, University “Ss Kiril and Metodij”, Skopje, Republic of Macedonia, Vanja Dzhambazovska-Trajkovska| Clinic of Anesthesiology, Reanimation and Intensive Care, Faculty of Medicine, University “Ss Kiril and Metodij”, Skopje, Republic of Macedonia, Marija Toleska| Clinic of Anesthesiology, Reanimation and Intensive Care, Faculty of Medicine, University “Ss Kiril and Metodij”, Skopje, Republic of Macedonia, Aleksandar Dimov| Clinic of Anesthesiology, Reanimation and Intensive Care, Faculty of Medicine, University “Ss Kiril and Metodij”, Skopje, Republic of Macedonia
Keywords
Related Articles
- EP ID EP8728
- DOI 10.3889/MJMS.1857-5773.2010.0092
- Views 369
- Downloads 21
Sperm Immobilization Properties of Aqueous Ethanolic Extract of Hymenocardia Acida Stem Bark
Hymenocardia acida (Large red-heart) is widely used in Nigeria and many African countries, and has many therapeutic benefits. This study evaluated the sperm immobilization property of aqueous ethanolic extract of Hymen...
Quantitative Assessment of Postural Stability and Balance Between Persons with Lower Limb Amputation and Normal Subjects by using Dynamic Posturography
Background. The amputation of lower limb constitutes a major handicap which involves a functional and professional incapacity. Balance has been reported to be a better predictor of an individual’s engagement in physi...
Some Anatomic-Topographic Features of Common and Right Hepatic Ducts and their Constituents
Aim. Anatomic-topographic features of the common duct and ducts of the right functional liver are attributes of the diagnostic-surgical and transplantation liver practice. In connection with this notion, this study has...
Comment on the Publication: Lazarevik V, Kasapinov B. Medical Doctors’ Attitudes towards Pay-For-Reporting in Macedonia: A Web-Based Cross-Sectional Survey. Maced J Med Sci. 2012;5(4):437-443
We are truly glad for the interest in scientific approach towards the model for Payment-for- Activity (PPU), recently introduced in the Republic of Macedonia, taking in consideration that for the very first time a syst...
Intravenous Iron Is Effective and Safe in Correcting Anemia in Erythropoietin-Treated Hemodialysis Patients
Objectives: To study the effect of intravenous iron in the management of anemia in erythropoietin (EPO) treated hemodialysis patients with poor response to treatment with oral iron. Methods: Thirty-six patients (27 men...