Preference of Multivariate Analysis over Univariate Analysis in Lung Function Studies
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 3
Abstract
Multiple dependent and independent variables affect lung function tests. Hence univariate analysis is not appropriate. The main objectives of the study were to show the appropriateness of multivariate analysis for these types of studies, to know the exact quantification effects of factors on study variables and to study the interaction effects of factors. Eighty individuals between 29-59 years formed the study group. Using computerized spirometer, 3 study variables - Forced Expiratory Volume in 1st sec / Forced Vital Capacity , Forced Expiratory Flow rate 25-75% and Peak Expiratory Flow Rate, were determined and correlated to 3 factors - age, gender and height. Seven Models were formulated by different combinations of factors. Each Model was analysed by Multivariate analysis of Variance (MANOVA) which resulted Wilks’ Lamda (λ), Univariate ANOVA with full Factorial Experiments (2n ) and K-matrix with Bonferoni’s confidence interval. Geometric Mean was calculated from partial 2 values. This methodology is superior and exact compared to univariate analysis. Overall contribution of age in influencing study variables simultaneously is 67.4%, gender 88.3%, height 63.2%, age-gender 30.9%, age-height 28.2% and gender-height 31.5%. This effect quantification information is not available in literature as their analysis was by univariate analysis. All main effects and second order interaction effects of factors are significantly influencing study variables. It is concluded that multivariate analysis is preferred over univariate analysis in lung function studies.
Authors and Affiliations
Dr Kalavathi Lakshmipathy
Keywords
Related Articles
- EP ID EP507910
- DOI -
- Views 74
- Downloads 0
Fetal Triploidy Syndrome – A Case Report
The fetal triploidy syndrome presentations include intrauterine growth retardation, hydrocephalus, oligohydramnios, and cystic changes of the placenta. Although the majority of triploid conceptions abort spontaneously in...
Psychosomatic Assessment of Street Children: A Gorakhpur Experience
Introduction: The aim of this cross- sectional study was to assess the socio-demographic profile, psychosomatic disorders, nutritional status and health related problems of street children in Gorakhpur region. Methodolog...
Study of Emergency Intestinal Resection and Anastomosis in Adults
Aims and Objectives: (1) To study the emergency intestinal resection and anastomosis. (2) To study various intestinal pathologies for which emergency intestinal resection and anastomosis was performed. (3)To study variou...
Abbe’s Flap for Lip Reconstruction –Report of 2 Cases
Lip is special to the face in its morphology and position. This tissue is not found anywhere else in the body, thus making the repair of its lost structure that much more difficult to the operating surgeon. Upper lip def...
13 Year Follow Up of a Subject with Anterior Cruciate Ligament – Reconstruction, treated with Physiotherapy
The subject having undergone anterior Cruciate ligament – reconstructive surgery of – right knee with subsequent rehabilitation in a 12 weeks period resumed his pre injury level of daily activities and continued occasion...