Preliminary Assessment of Phytochemical Constituents and Antibacterial Activity of Crude Leaves Extracts of Simarouba glauca
Journal Title: Bioscience Discovery - Year 2017, Vol 8, Issue 1
Abstract
Simarouba glauca is well known as paradise tree in India and other parts of world. Natural products and their derivatives have historically been exploited as a valuable source of novel therapeutic agents. Medicinal plants play a significant role in the production of novel and valuable drugs used in modern medicine. In present study the primary detection of important phytochemical properties of Simarouba glauca was attempted. In phytochemical analysis of crude leaves extracts of Simarouba glauca showed presence of carbohydrates, amino acids, proteins, glycosides, tannins, terpenoids, phenols and saponins. This study was also conducted to determine the antibacterial potential of crude leaves extracts of plant against Gram positive and Gram negative clinical isolates. The acetone extract showed remarkable antibacterial potential against test isolates. It exhibited higher zones of inhibition against E.coli and Salmonella paratyphi B i.e. 13 and 12 mm respectively. The Gram negative test organisms were found more susceptible as compared to Gram positive to acetone and methanol extracts.
Authors and Affiliations
Rajendrabhai D. Vasait1 and Kirankumar Khandare2
Keywords
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