Preliminary Characterization of Novel Gum Obtained from Myrianthus arboreus Leaves as Pharmaceutical Excipient

Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2017, Vol 3, Issue 11

Abstract

Abstract:Polymeric materials obtained from plant sources have become very versatile excipients for the formulation of pharmaceutical dosage form especially tablet dosage form. This study was aimed at the preliminary characterization of Myrianthus arboreus gum as pharmaceutical excipient. Myrianthus arboreus gum wasextracted from the dried powdered leaves of Myrianthus arboreus plant and characterized based on parameters such as micromeritic properties, phytochemical evaluation, viscosity, loss on drying, solubility, ash value and swelling index. The results obtained from this study showed a yield of gum after extraction of 11.34 % and swelling index of 97.63 % after 48 hours. A 1 % w/v dispersion of gum gave pH and viscosity values of 6.73 and 4,333 mPa•s respectively. Myrianthus arboreus gum exhibited fairly good flow properties with angle of repose of 31.65 º, bulk and tapped densities of 0.46 and 0.62 g/ml respectively and Carr’s index value of 25.33 %. The gum was found to swell in cold water, soluble in hot water and insoluble in organic solvents. It can be concluded therefore that Myrianthus arboreus gum could possibly be used as pharmaceutical excipient for the formulation of liquid and solid dosage forms. Keywords:Myrianthus arboreus, Pharmaceutical excipient, Gum, Dosage forms

Authors and Affiliations

Alalor CA, Emoredo A, Okafo SE

Keywords

Related Articles

Efficacy of Intermittent and Continuous Subglottic Secretion Drainage in Ventilator-Associated Pneumonia Reduction among Critically Ill Ventilated Patients: An Integrative Review

Abstract: Ventilator-associated pneumonia (VAP) is the most common nosocomial infection in critical care settings and affects between 9%-27% of mechanically ventilated patients for more than 48 or 72 hours. One of the st...

Antioxidant and Anti-Inflammatory Activity of ArthrospiraplatensisVar. Lake Chad

Abstract:The objective of this study is to evaluate the antioxidant and anti-inflammatory activity of the aqueous extract of Arthrospiraplatensis var. Lake Chad, also call spirulina. A phytochemical screening of the aque...

Mineral Content and Chemical Composition of Napier (Pennisetumpurpureum) Grass

Abstract:Napier grass is a popular tropical grass, employed by farmers in livestock nutrition. In this work, the matrices of matured shoots of P. purpureum (schumach) commonly called Napier grass, were subjected to pr...

Evaluation of Milk Kinship Formation via Early Breast-Feeding

Abstract:Consanguinity constitutes one of the major health problems worldwide, in which consanguineous marriages are associated with an increased risk for congenital malformations and autosomal recessive diseases. Althou...

Barriers to Reporting Medication Administration Errors among Nurses in Services Hospital Lahore

Abstract:According to the report of Institute of Medicine (IOM) that about 7,000 of death are occur annual because of the medication error which is going worse day by day. The effect of medication error is not good for p...

Download PDF file
  • EP ID EP393595
  • DOI -
  • Views 42
  • Downloads 0

How To Cite

Alalor CA, Emoredo A, Okafo SE (2017). Preliminary Characterization of Novel Gum Obtained from Myrianthus arboreus Leaves as Pharmaceutical Excipient. Saudi Journal of Medical and Pharmaceutical Sciences, 3(11), 1156-1161. https://europub.co.uk/articles/-A-393595