PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND IN VITRO ANTIMICROBIAL ACTIVITY OF ETHANOLIC EXTRACT OF SONNERATIA APETALA PLANT
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2013, Vol 4, Issue 6
Abstract
The aim of present study is to investigate the phytochemical constituents and antimicrobial activity of Ethanolic extract of Sonneratia apetala. Preliminary Phytochemical tests revealed the presence of alkaloids, flavonoids, tannins, saponins, phytosterols and carbohydrates. Antimicrobial activity was evaluated by Agar well Diffusion method. In vitro screening of Sonneratia apetala mangrove Ethanolic plant extract showed species specific activity in inhibiting growth of bacteria and fungi. The Ethanolic plant extract showed good activity against selected gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus, Staphylococcus werneri), gram-negative bacteria (Pseudomonas putida, Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumonia) and fungal strain (Candida albicans). The observations revealed significant zone of inhibition and supports to antimicrobial activity. The bioactive compounds responsible for these antimicrobial activities could be isolated and identified to develop a new drug of pharmaceutical interest.
Authors and Affiliations
Prabhu Teja, K. Ravishankar
Keywords
Related Articles
- EP ID EP109443
- DOI 10.7897/2230-8407.04619
- Views 100
- Downloads 0
DETERMINATION OF PERMEATION PATHWAY OF GENTAMICIN INTO PIG’S EAR SKIN
Extensive research has been conducted in the recent years with a focus on drug administration via the skin for both topical and systemic drug delivery. Understanding the drug permeation through the skin is crucial for th...
ANTIDIABETIC ACTIVITY OF ALANGIUM SALVIFOLIUM IN ALLOXAN INDUCED DIABETIC RATS
Alangium salvifolium is a commonly known herb in Indian system of medicine to treat various disorders including diabetes mellitus without any scientific evidences. Therefore this study was designed to investigate in vivo...
PHOTOSTABILITY TESTING OF PHARMACEUTICAL PRODUCTS
Stability testing is a key aspect while formulating any pharmaceutical product. The photostability studies are conducted with main objective that appropriate light exposure does not leads to unacceptable changes in dosag...
STUDIES ON ANTIASTHMATIC ACTIVITY OF AQUEOUS EXTRACT OF ROOTS OF MIMOSA PUDICA LINN
The present study designed to evaluate the antiasthmatic activity of aqueous extract of Mimosa pudica (AEMP) on in vitro and in vivo animal models. Histamine induced contraction in isolated goat tracheal chain showed th...
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF SIMVASTATIN AND SITAGLIPTIN
A simple, specific, accurate, rapid, inexpensive isocratic Reversed Phase-High Performance Liquid Chromatography (RP-HPLC) method was developed and validated for the quantitative determination of Simvastatin and Sitaglip...