PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND IN VITRO ANTIMICROBIAL ACTIVITY OF ETHANOLIC EXTRACT OF SONNERATIA APETALA PLANT
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2013, Vol 4, Issue 6
Abstract
The aim of present study is to investigate the phytochemical constituents and antimicrobial activity of Ethanolic extract of Sonneratia apetala. Preliminary Phytochemical tests revealed the presence of alkaloids, flavonoids, tannins, saponins, phytosterols and carbohydrates. Antimicrobial activity was evaluated by Agar well Diffusion method. In vitro screening of Sonneratia apetala mangrove Ethanolic plant extract showed species specific activity in inhibiting growth of bacteria and fungi. The Ethanolic plant extract showed good activity against selected gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus, Staphylococcus werneri), gram-negative bacteria (Pseudomonas putida, Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumonia) and fungal strain (Candida albicans). The observations revealed significant zone of inhibition and supports to antimicrobial activity. The bioactive compounds responsible for these antimicrobial activities could be isolated and identified to develop a new drug of pharmaceutical interest.
Authors and Affiliations
Prabhu Teja, K. Ravishankar
Keywords
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