PRELIMINARY PHYTOCHEMICAL SCREENING AND STANDARDISATION OF LEAVES OF CATHARANTHUS ROSEUS (L.) G. DON
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 1
Abstract
Catharanthus roseus (L.) G. Don (Periwinkle) belongs to the family Apocyanaceae, is a bushy perennial herb and evergreen shrub. More than 100 alkaloids and related compounds have so far been isolated and characterized from the plant. Main alkaloids are vincristine and vinblastine which are responsible for anticancerous activity. The present study deals with phytochemical screening, standardization and transverse section of the plant leaf. The dried leaves of Periwinkle were subjected for different standardization parameters like Total ash (0.4%), Acid insoluble ash (0.68%), Water soluble ash (1.68%), Sulphated ash (4.12%), Water soluble extractive (6.34%), Alcohol soluble extractive (4.8%), Moisture content (10.09%), Loss on drying (5.01%), Foaming index (0.9cm height) and Swelling index (0.8g) for their purity and strength as per WHO guideline. The Preliminary phytochemical screening report reveals the presence of Alkaloids, Glycosides, Terpenoids, Flavonoids, Phenols, Tannins, Carbohydrates, Saponins, Phytosterols, Protein and amino acids in ethanolic extract of the leaf of Catharanthus roseus (L.) G. Don . The transverse section of the plant exhibits small layer of rectangular cells covered with thick cuticle, uni-cellular covering trichome and vascular bundle present in the middle of midrib region and cruciferous stomata. This phytochemical standardization study will improvise the further research on this plant.
Authors and Affiliations
G. DON, Shambaditya Goswami
Keywords
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