Preloading or Coloading of Crysralloid for Prevention of Hypotension during Ceaserian Section under Spinal Anaesthesia, a Randomisd Control Trial
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 4
Abstract
Background: Hypotension after spinal anesthesia for cesarean delivery is common. Previous studies have demonstrated that a crystalloid fluid “coload” (rapid administration of a fluid bolus starting at the time of intrathecal injection) is superior to the conventional crystalloid preload (fluid administered before the intrathecal injection) for preventing hypotension. However there is paucity of study on the effectiveness or otherwise of coloading as against the common practice of crystalloid preloading for ceaserian section under subarachnoid block. This study compared crystalloid preloading to coloading in preventing hypotension usually associated with subarachnoid block for ceaserian section Methods: In this double-blind study, 60 patients were randomly assigned to receive a preload of 1L of normal saline over a period of 15–20 min before initiation of spinal anesthesia or an identical fluid (bolus of normal saline) starting at the time of identification of cerebrospinal fluid. Vasopressors (ephedrine) were administered if systolic arterial blood pressure decreased less than 80% of the baseline pressure and <100 mm Hg. The primary outcome was the incidence of hypotension (defined as the administration of at least one dose of vasopressor). Other complications like nausea and vomiting were also sought for. Results: There was no significant difference in the two groups in the incidence of hypotension (p= 0.823), nausea and vomiting and vasopressor requirements. Conclusion: There is no difference in the incidence of hypotension whether patients were coloaded or preloaded.
Authors and Affiliations
Olajumoke T. O, Owojuyigbe A. F, Afolayan J. M, Adekunle M. O
Keywords
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