Premorbid Cognitive Dysfunction and Endophenotypes in Bipolar Disorder: A Rapid Review
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2019, Vol 15, Issue 5
Abstract
On the contrary that happened with schizophrenia, it has not been completely clarify if cognitive alterations precede the illness or are a consequence of it. Although some data indicate that some cognitive deficits are already present before the illness begins, more studies are still needed.The poor existing evidence about these aspect indicated that premorbid bipolars patients did not show significate cognitive execution differences versus controls but they did versus premorbid schizophrenics [1] (even thought, these subjects were evaluated by a cognitive battery designed more for military purposes than clinical). Other studies have shown similar data, noting that, in contrast to other pathologies, severe premorbid cognitive dysfunction is not a dominant feature in bipolar disorder [2]. In general, these data would indicate that, if there is a premorbid cognitive malfunction, this would be mild or moderate. Other studies show that the severity of cognitive deficits in high-risk youth for bipolar disorder was relatively less pronounced compared to high-risk youth for schizophrenia, except for psychomotor speed, sustained attention and some executive aspects such as those based on the interference Stroop tests. Unlike schizophrenia, deficits in planning and working memory are not considered as factors of cognitive vulnerability.
Authors and Affiliations
J D Molina, E García Laredo
Keywords
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- EP ID EP587570
- DOI 10.26717/BJSTR.2019.15.002794
- Views 142
- Downloads 0
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