PREPARATION AND EVALUATION OF IMMEDIATE RELEASE GLICLAZIDE TABLET USING SUPER DISINTEGRANTS
Journal Title: International Journal of Pharmacognosy - Year 2018, Vol 5, Issue 5
Abstract
The present investigation was designed to prepare immediate release tablets of gliclazide with the ultimate aim of reducing the time needed to obtain the peak plasma concentration. Gliclazide immediate release tablets were prepared by using superdisintegrants namely- sodium starch glycolate and croscarmellose sodium. The prepared tablets were evaluated for weight variation, hardness, friability, and dissolution. Data obtained from in-vitro dissolution tests were employed to zero order kinetic model. All the data were in the acceptable range. Compatibility study was conducted using fourier transform infrared spectroscopy (FTIR). The drug and all the excipients showed good compatibility.
Authors and Affiliations
Tushar Saha
Keywords
Related Articles
- EP ID EP431983
- DOI -
- Views 73
- Downloads 0
PRELIMINARY PHYTOCHEMICAL SCREENING OF TWO MEDICINAL PLANTS -SOLANUM NIGRUM LINN. AND LEUCAS ASPERA (WILLD.) LINN.
The medicinal plants are useful for healing, as well as, for curing of human diseases because of the presence of phytochemical constituents. Phytochemicals are naturally occurring in the medicinal plants, leaves, vegetab...
COMPARATIVE STANDARDIZATION STUDY OF GANDHARVA HARITAKI CHURNA FORMULATION
Standardization is the need of the hour in Ayurvedic system of medicine. The traditional systems of medicine are really effective but the problem with them is they lack in quality assurance. This enables us to recognise...
PLANT PROFILE, PHYTOCHEMISTRY AND PHARMACOLOGY OF BAUHINIA VARIEGATA LINN. (KACHNAR): AN-OVERVIEW
Bauhinia Variegata Linn. is a widely used medicinal plant distributed in the tropical regions throughout the world. Its various part i.e. flowers, flower buds, stem, roots, stem bark, seeds, leaves have been used since a...
UV-VISIBLE SPECTROPHOTOMETRIC ESTIMATION OF CURCUMIN IN NANOFORMULATION
A rapid, simple, selective and precise UV-Visible spectrophotometric method has been developed for the determination of Curcumin in bulk and nano-formulation. The spectrophotometric detection was carried out at an absorp...
A STUDY ON THE INDIGENOUS MEDICINAL PLANTS AND HEALING PRACTICES OF MURONG TRIBE IN KHAGRACHARI DISTRICT (BANGLADESH)
An ethnomedicinal survey was carried out during August 2008 to October 2008 among tribal medicinal practitioners of the Murong tribes. Various Murong tribal practitioners practiced in their localities for treating differ...