PREPARATION AND EVALUATION OF IMMEDIATE RELEASE GLICLAZIDE TABLET USING SUPER DISINTEGRANTS
Journal Title: International Journal of Pharmacognosy - Year 2018, Vol 5, Issue 5
Abstract
The present investigation was designed to prepare immediate release tablets of gliclazide with the ultimate aim of reducing the time needed to obtain the peak plasma concentration. Gliclazide immediate release tablets were prepared by using superdisintegrants namely- sodium starch glycolate and croscarmellose sodium. The prepared tablets were evaluated for weight variation, hardness, friability, and dissolution. Data obtained from in-vitro dissolution tests were employed to zero order kinetic model. All the data were in the acceptable range. Compatibility study was conducted using fourier transform infrared spectroscopy (FTIR). The drug and all the excipients showed good compatibility.
Authors and Affiliations
Tushar Saha
Keywords
Related Articles
- EP ID EP431983
- DOI -
- Views 52
- Downloads 0
BIOLOGICAL ACTIVITIES OF EXTRACTS AND SEASONAL VARIATION IN ESSENTIAL OIL COMPOSITION FROM MYRCIARIA GLAZIOVIANA (MYRTACEAE)
Extracts from leaves, stems and flower buds of Myrciaria glazioviana were analysed for their antioxidant and anticholinesterase activity. The methanolic extracts showed the best results in reducing power (623.52 - 806.15...
A REVIEW ON PHARMACOLOGICAL AND THERAPEUTIC PROPERTIES OF ECHINACEA
The botanical supplement market is growing at a rapid rate and this trend is expected to continue to progress. In the world of Nutraceuticals Echinacea plant is widely used for medicinal and commercial purposes. This Nat...
PREPARATION AND EVALUATION OF POLYHERBAL FORMULATION FOR ITS ANTIDIABETIC ACTIVITY AGAINST STREPTOZOTOCIN INDUCED DIABETES RAT MODEL
The present work was executed to evaluate the anti-diabetic potency of a polyherbal preparation. The objective of this study is to induce experimental diabetes mellitus using streptozotocin in normal Albino wistar rats a...
GREEN NANOPARTICLE SYNTHESIS AND THEIR APPLICATIONS
As we are well aware that the production of metallic nanoparticles by the physical and chemical method has numerous drawbacks along with the use of toxic chemicals, high energy expenditure and non- biodegradable products...
ALTITUDE HEALTH PROBLEMS AND THEIR REMEDIES
People, who have visits to high altitudes, do experience certain type of health problems as they transits to different altitude ranges. With ascend to high altitude, various kinds of acute and chronic physiological chang...