PREPARATION AND EVALUATION OF MICROEMULSIONCONTAINING CLOVE OIL AND PEPPERMINT OIL AS ACTIVE COMPOUND
Journal Title: Journal of Pharmaceutical and Scientific Innovation - Year 2019, Vol 8, Issue 4
Abstract
Microemulsion are one of the potential and emerging drug carrier systems that helps to improve drug release and enhance the bioavailability of poorly aqueous soluble drugs. This study was designed to formulate and evaluate microemulsion containing clove oil and peppermint oil. Microemulsion was prepared using tween 80 as a surfactant and ethanol as a co - surfactant. The microemulsion formulation characterized for its particle size, viscosity, conductivity, pH, zeta potential and stability.The mean droplet size of clove oil and peppermint oil microemulsion was found in the range of 11-96nm and 11-68nm. The viscosity of the prepared microemulsions were found to be low. In the stability study there are no phase separation occur after centrifuged at 3000 RPM for 30 min and even after stored for 30 days.
Authors and Affiliations
Arabinda Changmai, Atul Adhikari, Biplab Kumar Dey
Keywords
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- EP ID EP649435
- DOI 10.7897/2277-4572.084145
- Views 55
- Downloads 0
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