Preparation Modification and Characterization of a Hydrogel Based on Polyacrylic and Polymetacrylic Acid as a Potential Carrier for Drug Delivery Systems
Journal Title: Open Access Journal of Pharmaceutical Research - Year 2017, Vol 1, Issue 2
Abstract
Complexes of polyacrylic acid (PAA) and polymethacrylic acid (PMA) in presence of sodium alginate (SAL) during redox polymerization of polyacids were formed. They were characterized by IR spectroscopy and viscometry. The swelling index of hydrogels based on the polymethacrylic acid-sodium alginate complex (PMA-SAL) has been found to be lower than that of polyacrylic acid-sodium alginate (PAA-SAL) complex. The hydrogels based on the complex of crosslinked polyacids with sodium alginate can be of practical interest as polymeric carriers for drugs
Authors and Affiliations
Voycheva C*, Georgiev V, Natova M and Baranovsky VY
Keywords
Related Articles
- EP ID EP745760
- DOI 10.23880/oajpr-16000112
- Views 17
- Downloads 0
Pharmacovigilance - Shaping the Present and Future of Medicines
Pharmacovigilance has an important role in detecting adverse drug reactions. The success of the programme depends on the knowledge and attitude of the involved professionals. Strong Pharmacovigilance programme will help...
Benzimidazole:- A Versatile Moiety
Benzimidazole is a promising nitrogen-containing nucleus with extensive pharmacological activity, some of which are listed in this article, such as antiprotozoal, anthelmintic, antipsychotic, antiparasitic, antifungal,...
Algae Therapy: Highlights on the Pharmaceutical Potentials of Algae
The markets for prescribed drugs are growing quickly worldwide. A developing share of today’s promising pharmaceutical research focuses on the manufacturing of effective bioactive compounds from algae. Pharmaceutically...
Highlights on the Wood Blue-Leg Mushroom Clitocybe Nuda and Blue-Milk Mushroom Lactarius Indigo Ecology and Biological Activities
The need to improve the life quality together with the increase in the frequency of treating diseases attracted the attention of many researches to view food as a source of nutritional and therapeutical agents. Since ea...
Assessment of CBC Changes in Breast Cancer Patients Following Treatment with 5-Flourouracil, Adriamycin and Cyclophosphamide (FAC-Protocol) and Adriamycin and Cyclophosphamide (AC-Protocol)
Objective: FAC (5 fluorouracil, Adriamycin and cyclophosphamide) and AC (Adriamycin and cyclophosphamide) protocols have significant anti-tumor activity in patients with breast cancer. Our objective was to evaluate the C...