Prescription pattern of anti-epileptic medications in a tertiary care centre
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2018, Vol 5, Issue 1
Abstract
Introduction The objective of this study was to study the prescribing pattern of antiepileptic medications in patients with epilepsy in a tertiary care hospitalMaterials and Methods This was an observational study conducted in psychiatry outpatient department OPD of Bapuji attached to Jagadguru Jayadeva Murugarajendra medical college and CG Hospital Davangere Patients demographic details clinical diagnosis type of epilepsy type of AED used drug dose and frequency of 100 outpatients who attended the psychiatry OPD was recordedResults A total of 100 prescriptions were analysed with more number of males 62 than females 38 Epilepsy was more commonly seen in the patients of age group of 2040 years 52 and GTCS was diagnosed in 79 of the patients followed by partial seizures and other types Majority of them received monotherapy 67 with most commonly prescribed AED phenobarbitone 28 followed by phenytoin 16 levetiracetam 12 carbamazepine 8 lorazepam 2 and ethosuximide 1 33 of the patients received combined therapy most commonly used two drug combination was phenobarbitone with phenytoin and three drug combination was with phenobarbitone phenytoin and carbamazepine 19 patients reported adverse events most common were related to CNSConclusion In our study majority of the patients were males with age group 2040 yrs and most commonly used drugs were conventional AEDs as monotherapy with phenobarbitone phenytoin and levetiracetamKeywords Epilepsy Anti Epileptic Drug AED Monotherapy Combined therapy Prescribing patternnbsp
Authors and Affiliations
Shilpa B. N. , Sushma H. K. , Latha S. , Shashikala G. H.
Keywords
Related Articles
- EP ID EP478530
- DOI 10.18231/2393-9087.2018.0003
- Views 66
- Downloads 0
Hypolipidemic activity of Lannea coromandelica Houtt. leaves in Triton X-100 induced hyperlipidemic rats
Lannea coromandelicaHoutt have multiple pharmacological activities including antiinflammatory aphrodisiac hypotensive anti microbial ulcerative stomatitis wound healing leprosy gout elephantiasis and cholera Therefore th...
Evaluation of antidepressant effects of rosuvastatin in male albino mice by tail suspension model
Objective: To evaluate the antidepressant activity of Rosuvastatin in male albino mice. Method: Thirty male swiss albino mice were selected for tail suspension model. There were five groups and each group had six animals...
Evaluation of Efficacy of Nevirapine Regimen versus Efavirenz Regimen
Introduction: CD4 count can be used as marker to assess the effectiveness of antiretro viral treatment (ART), mortality and survival rates in HIV patients. It is an important guide to treatment as it reflects drug resist...
Antihyperlipidemic Effect of Microbially Converted Eicosapentaenoic Acid from Rice Bran Oil in Rats
Objective: Eicosapentaenoic acid (EPA) from fish oil is known to have favourable effects on cardiovascular system by lowering the elevated lipid levels. With the intention of producing an alternative vegetarian source to...
Evaluation and comparison of hypoglycemic activity of bark and leaf of Ficus bengalensis linn. in alloxan induced diabetes in albino rats
Objectives: Evaluation of Hypoglycemic activity of Extract of bark and leaf of Ficus bengalensis Linn.in alloxan induced diabetic albino rats and comparison with standard antihyperglycemic drug Glibenclamide. Materials a...