Prescription pattern of anti-epileptic medications in a tertiary care centre
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2018, Vol 5, Issue 1
Abstract
Introduction The objective of this study was to study the prescribing pattern of antiepileptic medications in patients with epilepsy in a tertiary care hospitalMaterials and Methods This was an observational study conducted in psychiatry outpatient department OPD of Bapuji attached to Jagadguru Jayadeva Murugarajendra medical college and CG Hospital Davangere Patients demographic details clinical diagnosis type of epilepsy type of AED used drug dose and frequency of 100 outpatients who attended the psychiatry OPD was recordedResults A total of 100 prescriptions were analysed with more number of males 62 than females 38 Epilepsy was more commonly seen in the patients of age group of 2040 years 52 and GTCS was diagnosed in 79 of the patients followed by partial seizures and other types Majority of them received monotherapy 67 with most commonly prescribed AED phenobarbitone 28 followed by phenytoin 16 levetiracetam 12 carbamazepine 8 lorazepam 2 and ethosuximide 1 33 of the patients received combined therapy most commonly used two drug combination was phenobarbitone with phenytoin and three drug combination was with phenobarbitone phenytoin and carbamazepine 19 patients reported adverse events most common were related to CNSConclusion In our study majority of the patients were males with age group 2040 yrs and most commonly used drugs were conventional AEDs as monotherapy with phenobarbitone phenytoin and levetiracetamKeywords Epilepsy Anti Epileptic Drug AED Monotherapy Combined therapy Prescribing patternnbsp
Authors and Affiliations
Shilpa B. N. , Sushma H. K. , Latha S. , Shashikala G. H.
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