PRESCRIPTION PATTERNS OF ANTIHYPERTENSIVE DRUGS AND ADHERENCE TO JNC VII GUIDELINES IN A TERTIARY CARE HOSPITAL IN NORTH INDIA
Journal Title: International Journal of Medical and Clinical Research - Year 2012, Vol 3, Issue 2
Abstract
Introduction Hypertension is a chronic illness associated with high morbidity & mortality. A large number of antihypertensive drugs alone or in various combinations are available and physicians need to choose the most appropriate drug for a particular patient. The standard treatment guidelines and drug utilization studies at regular intervals help physicians to prescribe drugs rationally. The present study was conducted to analyze the prescription patterns of antihypertensive drugs and adherence to JNC VII guidelines in a North Indian tertiary care hospital. Methods Drug utilization data of 500 hypertensive patients, attending medicine Out Patient Department of Punjab Institute of Medical Sciences Hospital from October 2010 to March 2011 was collected from 24 hour hospital pharmacy. Following groups of anti hypertensive drugs were analyzed; Angiotensin converting enzyme inhibitors (ACE inhibitors), Angiotensin Receptor Blockers (ARBs), Beta Blockers, Calcium Channel Blockers (CCBs), Diuretics, Alpha Adrenergic Blockers and Central Sympatholytics. Patients suffering from essential hypertension with or without other co-morbid conditions were included in the study. Frequency and proportion of prescribing different groups of anti hypertensive drugs as monotherapy or combination therapy and prescription of fixed drug combinations (FDCs) was analyzed. Results The most frequently prescribed antihypertensive drugs were diuretics followed by ARBs, Beta Blockers, CCB’s and ACE inhibitors. 42.6% received monotherapy and 57.4% received combination therapy. 41.6% patients received fixed drug combinations. The prescription pattern was found to be in accordance with JNC VII guidelines.
Authors and Affiliations
M SOOD, J. K. BAJAJ, S. J. SINGH, P. JERATH
Keywords
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- EP ID EP170047
- DOI 10.9735/0976-5530.3.2.118-120
- Views 125
- Downloads 0
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