PRESENCE AND SIGNIFICANCE OF MICRO-ORGANISMS IN OPEN FRACTURES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 14
Abstract
BACKGROUND Open fractures with bony injuries should be fixed urgently to prevent further injury and pain. Consideration of skin and soft tissue injuries along with the presence of infection by myriad of bacteria pose a threat by delaying wound healing and worsening of prognosis. The aim of this study was to find out the different types of micro-organisms contaminating open fractures along with their antimicrobial susceptibility pattern. MATERIALS AND METHODS The study was a prospective observational study conducted in Medical College, Kolkata for a period of one and a half years (March 2016 to August 2017). Cases selected in the Department of Orthopaedics and Casualty were those who had open fractures of duration of presentation of less than 1 day. Wound swabs were taken from the depth of the wound and sent to the Department of Microbiology for isolation, identification and antimicrobial susceptibility testing of the causative micro-organisms. Repeat swabs were taken on 3rd, 5th, 7th and 10th days after presentation during each debridement. RESULTS A total number of 400 patients were included in this study during the period of 1.5 years. The mechanism of injury was mostly road or rail traffic accidents in 232 (58%) cases. Maximum number of open fractures were sustained in leg, comprising 169 (42.25%) followed by forearm of 106 (26.5%) cases. The most common organisms were Staphylococci, Enterobacteriaceae and Pseudomonas. Staphylococcus and Enterococcus were highly susceptible to vancomycin and linezolid. The Gram negative organisms were susceptible to imipenem, meropenem and colistin. CONCLUSION It is pertinent to know the microbial organisms in open fractures for judicial use of antibiotics only after proper culture and sensitivity report to prevent emergence of more resistant strains of pathogens.
Authors and Affiliations
Sambit Acharya, Mallika Sengupta, Soma Sarkar, Atreyi Chakroborty, Aniruddha Sengupta, Manideepa Sengupta
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