Preterm Prelabour Rupture of Membranes at 34-37 Weeks’ Gestation: Intentional Delivery versus Expectant Management
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 6
Abstract
Objectives: In this prospective study we wanted to prove that intentional delivery as compared to expectant management for PPROM at 34 – 37 weeks’ gestation will be associated with improved maternal and perinatal outcome. Study Design: Consecutive 100 gravid women at >34 weeks 0 days and <36 weeks 6 days of gestation attending the labour emergency with PPROM fulfilling the selection criteria taken for study. They were randomized to receive misoprostol induction (n=50) or expectant (n=50) treatment only. Result: In this study 12% women of expectant group developed chorioamnionitis and no chorioamnionitis occurred in any women Of induction group (12% vs. 0%, p=0.0353). Maternal hospital stay was significantly prolonged among patients in the expectant group (7.98±5.71 days vs. 3.28 ± 1.98 days, p=0.0001). Rate of Caesarean Section was more in induction group (16% vs. 10%, p= 0.5536). Birth Titol Biswas et al JMSCR Volume 2 Issue 6 June 2014 Page 1349 JMSCR Volume||2||Issue||6||Page 1348-1357 ||June 2014 2014 asphyxia (A.S < in 1 min) was more common in expectant group (14% vs. 10%, p=0.095), and neonatal sepsis also more common in expectant group (12% vs. 2%, p=0.1169). Conclusion: In women whose pregnancy is complicated by PPROM at 34 weeks 0 days to 36 weeks 6 days, our study indicates that intentional delivery by induction of labour substantially improves pregnancy outcomes compared with expectant management.
Authors and Affiliations
Titol Biswas
Keywords
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