Pretreatment with Ondansetron and Lignocaine for Alleviating Pain on Propofol Injection during Induction of Anaesthesia – A Comparative Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 11
Abstract
Background: Pain on injection of anaesthetic is an important cause of patient dissatisfaction and is a recognised adverse effect of propofol, incidence varying between 28 – 90% in adults. Methodology: It is a comparative study conducted on 120 patients of age 18-60 years, ASA Grade I and II, randomly allocated to two groups L and O of 60, each receiving lignocaine(L) and ondansetron(O) respectively for 3 years at Department of Anaesthesia, Osmania General Hospital using Mc Crirrick and Hunter scale. Results: Both lignocaine and ondansetron were found to decrease the injection pain significantly i.e. 73% of patients in L group & 63.3% O group did not experience pain at all, 11.7% L group and 20% in O group had mild pain, 13.3% in L group and 16.7% in O group had moderate pain, severe pain was absent in both groups. 26.7% of patients in group L and 10% of patients in group O complained of nausea and vomiting within 24hr postoperative period. The incidence of Postoperative nausea and vomiting was less in ondansetron group. Conclusion: Ondansetron decreases the injection pain significantly. Ondansetron has an added advantage of decreasing Postoperative nausea and vomiting.
Authors and Affiliations
Dr. C Parikshith, Dr. Rakam Kalyan
Keywords
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- EP ID EP238864
- DOI 10.9790/0853-1611076468
- Views 105
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