Prevalence and Antibiogram of Methicillin Resistant Staphylococcus aureus Isolates in a Tertiary Care Centre of Western Uttar Pradesh
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 9
Abstract
Methicillin resistant Staphylococcus aureus (MRSA) infections have emerged as one of the most common healthcare acquired infections in the present era. In this study, we report the prevalence and antibiotic susceptibility pattern of MRSA isolates from various clinical samples in a tertiary care hospital. Various clinical specimens from both outpatients as well as admitted patients were cultured on the suitable culture media and Staphylococcus aureus was identified using standard tests like catalase test, slide and tube coagulase test. All Staphylococcus aureus isolates were tested for their antibiogram pattern by Kirby - Bauer disc diffusion method and MRSA were identified amongst them following CLSI guidelines. The Dtest was performed on all Staphylococcus aureus isolates to identify erythromycin induced clindamycin resistance. The prevalence of MRSA in our study was found to be 60.87%. Linezolid and vancomycin proved to be effective against 96.4% and 100% of MRSA isolates respectively.. Antibiotics with highest resistance against MRSA isolates were penicillin, quinolones (ciprofloxacin, levofloxacin) and ampicillin. Also, 32.14% of MRSA isolates and 22.22% of MSSA isolates showed erythromycin induced clindamycin resistance in this study. Regular surveillance of hospital associated infections along with strict infection control measures, monitoring antibiotic susceptibility pattern of all MRSA isolates and formulation of definite antibiotic policy should be implemented in the hospitals as control measures against MRSA infections.
Authors and Affiliations
Dr Vijay Prakash Singh
Keywords
Related Articles
- EP ID EP515714
- DOI -
- Views 46
- Downloads 0
Estimation of Body Stature Using Fore Arm Bone (ULNA) – A Cross Sectional Study
Background- Stature is natural heights of a person in an upright position. Estimation of body stature has a chief importance in the field of anthropometry and forensic science research. In this connection, I have made an...
Brain Metastasis in Carcinoma Gallbladder – A Rare Case Report
Gallbladder cancer is an aggressive cancer with early dissemination to liver and lymph nodes, but metastasis to brain is rare. Here, we described a case of gallbladder cancer which subsequently developed brain metastasis...
Pulsatile Neck: A Rare Case Report
Common carotid artery aneurysms are rare but lethal whenever present. Early diagnosis and adequate treatment is required in order to prevent rupture or neurologic sequelae. We represent a rare case of asymptomatic pulsat...
Screening of Aminoacidurias in Children
Inborn errors of metabolism (IEM) are genetically determined biochemical disorders due to specific congenital defects in protein molecules. In infants and young children the inborn errors produce mental deficiency and se...
A Study on Antibodies against Salmonella Typhi and Paratyphi in a Healthy Adults Population at Kulasekharam, Tamil Nadu
Enteric fever remain as an important public health problem globally and it is a major cause of morbidity in the developing world. Typhoid fever is caused by Salmonella typhicc and a less severe disease, paratyphoid fever...