Prevalence and Antimicrobial Resistance Pattern of Bacterial Isolates in a Tertiary Care Hospital of Assam, India
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 2
Abstract
Background: Antimicrobial resistance (AMR) has emerged as a major public health problem all over the world. Infections caused by resistant microbes fail to respond to treatment, resulting in prolonged illness and greater risk of death. India is among the nations with the highest burden of bacterial infections. The crude mortality from infectious diseases in India today is 417 per 100,000 persons. The present study is undertaken with the object of find the prevalence of common organism isolated and drug resistance pattern in the isolates in a tertiary care hospital in Assam. Methods: A retrospective cross sectional study of non repeated samples of patients attending OPD and those admitted in different clinical departments. Antimicrobial susceptibility testing was performed using Kirby-Bauer’s disc diffusion method. MAR index of > 0.2 indicates that an organism must have originated from an environment where antibiotics are often used. Data analysis was done by using Microsoft excel 2007 and SPSS Statistical software package 16.0. Results: Out of 556 samples, 319 (57.4%) showed significant growth of organisms. most common organisms were staphylococcus aureas (38.9%). Amoxiclav, cephalosporin, flouroquinolone resistance demonstrated by all organisms. Compartatively less resistance to aminoglycosides, nitrofurantoin and 100% sensitive to Linezolid and Imipenem detected. Highest MAR index (>0.2) exhibited by E.Coli (80%). Conclusion: The fact that antibiotic use is increasing is not, itself, indicative of a problem, but evidence from studies of prescribing patterns suggests that antibiotics are often used in inappropriate ways. There is need of continuous AMR surveillance, effective infection control practices and adopt a suitable hospital antibiotic policy.
Authors and Affiliations
Ajit Kumar Dey
Keywords
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