Prevalence and Characterization of Thrombocytopenia in Pregnancy in Indian Women
Journal Title: International Journal Of Research In Medicine - Year 2016, Vol 5, Issue 4
Abstract
BACKGROUND: To determine the aetiology, prevalence and outcome of thrombocytopenia in pregnancy. Study design, settings and duration: An Observational hospital based study was conducted at B.J. Medical collage Ahmedabad, September 2014 to August 2015. PATIENTS AND METHODS: Total 6576 obstetric patients were admitted in Obstetrics & Gynaecology department during this period of whom 73 had thrombocytopenia in pregnancy. Depending on the number of platelets; thrombocytopenia was divided into four groups, i.e. those having platelets below 20,000, between 20-50,000, between 50-100,000 and more than 100,000. A predesigned structured proforma was used. RESULTS: The most common cause of thrombocytopenia was gestational thrombocytopenia seen in 26(33.8%) patients followed by HELLP syndrome19 (26.7%) and hepatitis E in 10(16.3%) patients. There were 11 cases who had platelets below 20,000, 18 had levels between 20-50,000 and 19 had between 50-1,00,000. The common symptoms were bleeding seen in 30(42.2%) cases and purpura or easy bruising seen in 11(15.4%) cases while, 30 cases were asymptomatic. Of 11 cases that had platelets below 20,000, 10 mothers died along with their 7 babies while, only 3 surviving babies were those of mothers dying of postpartum haemorrhage. Eighteen mothers had platelets between 20-50,000 and out of these 9 mothers and 11 neonates died. Nineteen mothers had platelets between 50-100,000 and out of these one mother and 3 neonates died. Overall maternal mortality was 20(28.1%). Maternal and fetal deaths occurred in almost all cases with DIC while, in PPH mothers died but their newborns survived irrespective of platelet count. CONCLUSION: Diseases causing platelets below 50,000 in pregnancy should be rated as high risk pregnancies and dealt with accordingly to reduce high foetal or maternal mortality.
Authors and Affiliations
Hina Oza, Mitesh Priydarshi , Nidhi Pancholi
Keywords
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