Prevalence and Severity of Amlodipine Induced Gingival Overgrowth
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 2
Abstract
Introduction: Amlodipine, a long-acting CCB, is a commonly used hypertension drug. Dihydropyridines are the agents most frequently implicated. All of them seem to act similarly on secondary target tissue, i.e., the gingival connective tissue, causing common clinical histo-pathological findings. This study was carried out with an aim to determine the prevalence of Amlodipine Induced Gingival Overgrowth (AIGO). It is also a concern for both the patient and the clinician due to its unaesthetic appearance and formation of new niches for periodontopathogenic bacteria. Material and methods: Prospective clinical study to assess prevalence and severity of Amlodipine induced Gingival Overgrowth in hypertensive patients attending Hypertension OPD in Government Stanley Medical College Hospital receiving amlodipine singly or in combination with other drugs not known to cause this effect. Results: It is interesting to note the incidence of ankle edema which is more known fact about the side effects of this calcium channel blocker was only 32percent as against 68percent of AIGO Conclusion: In this study 76% of the patients were found to have gingival overgrowth, of which there was a 68% incidence in females, 66% of patients were found to be over 50 years of age. No significant correlation was observed between age, gender, drug dosage and prevalence of gingival overgrowth.
Authors and Affiliations
R. Jayanthi, A. Mohammed Kalifa, B. M. Archana, Sindhiya Jayachandran, Flaicy Varghesse
Keywords
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