Prevalence and Severity of Amlodipine Induced Gingival Overgrowth
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 2
Abstract
Introduction: Amlodipine, a long-acting CCB, is a commonly used hypertension drug. Dihydropyridines are the agents most frequently implicated. All of them seem to act similarly on secondary target tissue, i.e., the gingival connective tissue, causing common clinical histo-pathological findings. This study was carried out with an aim to determine the prevalence of Amlodipine Induced Gingival Overgrowth (AIGO). It is also a concern for both the patient and the clinician due to its unaesthetic appearance and formation of new niches for periodontopathogenic bacteria. Material and methods: Prospective clinical study to assess prevalence and severity of Amlodipine induced Gingival Overgrowth in hypertensive patients attending Hypertension OPD in Government Stanley Medical College Hospital receiving amlodipine singly or in combination with other drugs not known to cause this effect. Results: It is interesting to note the incidence of ankle edema which is more known fact about the side effects of this calcium channel blocker was only 32percent as against 68percent of AIGO Conclusion: In this study 76% of the patients were found to have gingival overgrowth, of which there was a 68% incidence in females, 66% of patients were found to be over 50 years of age. No significant correlation was observed between age, gender, drug dosage and prevalence of gingival overgrowth.
Authors and Affiliations
R. Jayanthi, A. Mohammed Kalifa, B. M. Archana, Sindhiya Jayachandran, Flaicy Varghesse
Keywords
Related Articles
- EP ID EP425098
- DOI -
- Views 101
- Downloads 0
Triple Malignancy Involving Breast, Ovary and Uterine Vault: A Case Report and Literature Review
Introduction: The occurrence of two or more primary malignant neoplasms in the same person is rare. We have a case report of a 45-year-old woman with triple malignancy involving breast, ovary and uterine vault being mana...
Effect of Various Collagen Cross Linkers on the Bond Strength of Dentin Bonding Agents to the Dentin
Introduction: Improvement of the mechanical properties of type 1 collagen may be advantageous during bonding procedures. So various collagen cross linkers are used in this review which are responsible for modification of...
Icodextrin for Long Night Dwell in CAPD in Indian Patients – A Single Centre Experience
Introduction: Icodextrin is a glucose polymer derived from starch and has an average molecular weight of 20,000D. It was developed to overcome some of disadvantages of conventional dextrose solution in Continuous Ambulat...
Study on Role of CT in Cerebrovascular Accidents in a Tertiary Care Hospital
Introduction: Cerebrovascular accident is defined as sudden loss of blood circulation to an area of the brain resulting in a corresponding loss of neurologic function. The aim of the study was to evaluate the role of com...
Progressive Craniofacial Abnormality in a Case of Congenital Neurofibromatosis
Introduction: Neurofibromatosis is a generalized form of benign tumour of peripheral nerves, from fibrous element of nerve sheath. There are two types of neurofibromatosis, both being autosomal dominant. Type 1 also know...