Prevalence and staging of chronic kidney disease among adults in Chennai metropolitan area
Journal Title: Journal of the Indian Medical Association - Year 2018, Vol 116, Issue 2
Abstract
Chronic kidney disease (CKD) has been an emerging threat to the health care, due to the increasing burden of type 2 diabetes mellitus and hypertension. There are few studies in India done to assess the prevalence of CKD. This study was carried out to estimate the prevalence of CKD among adults in Chennai metropolitan area. This study was carried out as a cross sectional study in Chennai among 2796 adults. The sample was distributed among 15 administrative zones of Chennai Corporation and 2 administrative zones of Kanchipuram. We measured serum creatinine levels using isotope mass dilution spectroscopy (IDMS) calibration method, and estimated Glomerular Filtration Rate was calculated using the CKD-EPI equation, based on which CKD was classified into stages. The mean age of study participants was 46.16±13.22 years. About 3.9% had a serum creatinine >1.2 mg/dl, impaired GFR was significantly associated with age above 45 years (p=0.001), female sex (p=0.001), hypertension (p=0.001), and history of diabetes mellitus (p<0.001). The overall prevalence of CKD stage 3-5 by the CKD-EPI formula (<60 mL/mm/1.73m) was 4.24%. A comprehensive prevention programme to combat the risk factors should be in place as a part of public health infrastructure, in order to minimize morbidity, mortality and socioeconomic burden of chronic kidney disease. [J Indian Med
Authors and Affiliations
Rama Ravi, Rajeevalochana Parthasarathy, GEORGI ABRAHAM
Keywords
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