Prevalence Of Acute Hepatitis B Virus Infection Among Children With Liver Disease Admitted In A Public Tertiary Level Hospital In Dhaka
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 8
Abstract
Objective: This study was conducted to determine the prevalence of acute hepatitis B virus (HBV) infection among children admitted in Pediatric Gastro-enterology and Nutrition Department of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. The second objective was to identify the risk factors of HBV infection with target group for vaccination. Methodology: Children were selected purposively with liver disease presented with jaundice, abdominal distention, abdominal pain, fever, haematemesis and melaena. Result: Among the total participants 28(31.8%) were within the age range of 8.1 to 10 years, 25(28.4%) within 4 to 6 years and the least 10(11.4%) within 2 to 4 years. Out of the total studied children, 55(62.5%) were male and 33(37.5%) were female and M:F was 1.7:1. Among the 88 studied children, 11(12.5%) were found to be positive for HBsAg, 3(3.4%) for anti HBc-IgM, 1(1.1%) for both and both the tests were negative in 73(83.0%) children. Sixty one (69.3%) of the studied children were vaccinated against hepatitis B virus. Eleven children (12.5%) of the total had H/O blood transfusion/trauma/injection, 13(14.8%) had umbilical sepsis, 14(15.9%) underwent dental procedure, 10(11.4%) had previous surgery, and 23(26.1%) of the total male children had history of circumcision. Conclusion and recommendation: This study revealed that preschool children are high risk age group for HBV infection and horizontal transmission is possibly the major mode of transmission. Universal immunization coverage should be enhanced to reduce the incidence of HBV infection and this virus related chronic liver disease in children.
Authors and Affiliations
Dr. Kamrunnaher Shultana, Dr. Md. Mozammel Haque, Dr. Dhiman Chowdhury
Keywords
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- EP ID EP380913
- DOI 10.9790/0853-1708045155.
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