Prevalence of asymptomatic hepatitis B virus and hepatitis C virus infections in patients with maintenance hemodialysis of a tertiary care hospital in western Maharashtra
Journal Title: Indian Journal of Microbiology Research - Year 2018, Vol 5, Issue 3
Abstract
Introduction: Patients on Maintenance Hemodialysis (HD) are at high risk of viral hepatitis due to blood transfusion, prolonged vascular access, exposure to infected patients and contaminated equipments etc. Knowledge of the prevalence of such infections is very important to access magnitude of the problem because these infections play important role in the morbidity and mortality of hemodialysis (HD) patients. Aim and Objectives: This study was done to determine the prevalence of Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infections in patients on hemodialysis at our tertiary care hospital of Western Maharashtra. Materials and Methods: Settings and Design: Hospital based cross sectional study was conducted for six months in HD unit at our tertiary care hospital. All patients (n=135) were screened for Hepatitis B surface antigen and antibodies to HCV (anti-HCV). Prevalence, age and sex wise distribution as well as risk factors for transmission of these infections were observed. Results: Total 135 HD patients were screened for presence of HBV and HCV infections. Of these, 39 (28.9%), 20 (14.8%), 6 (4.4%) were found to be having HCV, HBV and Dual HBV and HCV infection respectively. Conclusions: HCV was the most prevalent among HD patients than HBV. History of multiple blood transfusions, HD outside center or longer duration of HD were all important risk factor noted for high prevalence of sero-positivity for HBV and/or HCV. Strict adherence to universal precautions careful attention to hygiene and strict sterilization of dialysis machines are important to prevent further transmission of these viruses.
Authors and Affiliations
Santosh Shankar Patil, Bipin Munjappa, Shubhangi A. Gadgil, Amit Gadve
Keywords
Related Articles
- EP ID EP472166
- DOI 10.18231/2394-5478.2018.0080
- Views 63
- Downloads 0
Prevalence and epidemiology of outbreaks of influenza A(H1N1)pdm09 virus in Gujarat from August 2009 to March 2016 with special reference to 2015 resurgence
Purpose: Influenza is a widespread viral infection and a major cause of morbidity and mortality worldwide. The present study was performed to investigate the Influenza A H1N1 2009 pandemic (influenza A(H1N1)pdm09) virus...
Characterisation and Antifungal susceptibility pattern of Candida species isolated from various clinical samples at a tertiary care centre in South India
Background: Over the last 20 years, the rates of fungal infection have increased and Candida has emerged as a major cause of human disease. Furthermore there is an increase in nonalbicans candida species in many countrie...
In vitro study of the antimicrobial property of Green tea extract against standard (ATCC) bacterial strains and clinical isolates of Methicillin Resistant Staphylococcus aureus & Multidrug Resistant P
Objective: To evaluate the antimicrobial activity of Aqueous Green Tea extract against Standard ATCC Strains (Staphylococcus aureus ATCC 25923, Escherichia coli 25922, Pseudomonas aeruginosa 27853) & Clinical Isolates of...
A study on Clinico-Epidemiological Profile of Bacterial infections in Intensive care unit and its implications on empiric therapy
Background: To study the bacteriological profile of infections in patients admitted to ICU and to determine the antibiotic susceptibility patterns of the bacterial isolates. This study was done as Prospective study of 2...
Mutagenesis and screening of Penicillium oxalicum (Dal 5) for enhancing cellulase production
In the modern era due to increasing fuel demand prices of crude oil is increasing day by days So the need for bioenergy sources is increasing in coming years Of all the biomass present in the world lignocelluloses as ind...