Prevalence of carbapenem resistant Enterobacteriaceae from a tertiary care hospital in Mumbai, India
Journal Title: Journal of Microbiology and Infectious Diseases - Year 2013, Vol 3, Issue 4
Abstract
Objective: The emergence of Carbapenem Resistant Enterobacteriaceae (CRE) in recent times has become a serious threat to public health due to the high mortality, potential dissemination rates and limited treatment options associated with these organisms. Thus, the present study was conducted in our tertiary care hospital in Mumbai, to retrospectively analyze the prevalence of CRE in the hospital. Methods: The study was carried out in the microbiology department of the tertiary care hospital over a period of 12 months. The samples tested were clinical samples from hospitalized and Out-Patient Department (OPD) patients sent to the department for microbiological testing. CRE isolates were identified using the Vitek 2- Compact system (BioMérieux, France). Results: A CRE prevalence rate of 12.26% was obtained from the study, from which the majority of the isolates were detected in urine samples (46%). Although most of the CRE isolates were detected in patient samples from the wards (42%) and the ICU (26%), a significant number of isolates was also detected from the OPD patients (19%). Conclusion: Thus, the study shows a significant rate of carbapenem resistance among Enterobacteriaceae isolated from hospitalized and OPD patients. This emphasizes the urgent need for CRE control at the hospital and community level, and to rationalize the use of antibiotics. J Microbiol Infect Dis 2013;3(4): 207-210 Key words: Carbapenem Resistant Enterobacteriaceae, Antimicrobial Stewardship
Authors and Affiliations
Pravin K. Nair, Michelle S Vaz
Soft Tissue Abscess due to Eikenella corrodens after Human Bite
Eikenella corrodens is found in oral, gastrointestinal and genitourinary normal flora. Eikenella species have been shown to cause serious human infections such as head-neck infection, pulmonary infection, arthritis...
Vankomisin dirençli enterokok’larda (VRE) vanA ve vanB gen prevalansının Taq Man real time PCR assay ile araştırılması
Amaç: Enterokoklar önemli hastane enfeksiyonu etkenidirler ve antimikrobiyal direnç potansiyelleri nedeniyle rezistans genlerinin yayılmasında önemli rolleri bulunmaktadır. Günümüzde bu mikroorganizmalar önemli bir halk...
Prognostic value of mean platelet volume and neutrophil to lymphocyte ratio in patients with Crimean-Congo Hemorrhagic Fever
Objective: Crimean-Congo hemorrhagic fever (CCHF) virus, a Nairovirus within the family Bunyaviridae, causes severe disease in humans. Pancytopenia, organ failures and disseminated intravascular coagulation may occur as...
HIV pozitif hastalarda koruyucu İzoniyazid tedavisinin kullanımı ve uyumla ilişkisi
Amaç: Latent tüberküloz enfeksiyonu olan bireylere aktif hastalığın ilerlemesini önlemek için İzoniyazid (INH) profilaksisi verilir. Uyumsuzluk ile ilişkili faktörleri anlamak profilaksi başarısı için önemlidir. Bu çalış...
Kolistin dirençli Acinetobacter baumannii ’ye bağlı sağlık bakımı ile ilişkili bir pnömoni vakası
Yetmiş sekiz yaşındaki erkek hasta ensefalopati tanısı ile nöroloji bölümüne yatırıldı. Ventilatör ilişkili pnömoni (VİP) nedeniyle başlanan imipenem tedavisinin 13. gününde fizik muayene, laboratuar ve radyolojik bulgul...