Prevalence of Dengue with Its Pathological Co-Relation at Sentinel Surveillance Unit, Palanpur
Journal Title: Saudi Journal of Pathology and Microbiology - Year 2018, Vol 3, Issue 10
Abstract
Dengue, one of the world’s major emerging tropical viral disease, is a significant cause of morbidity and mortality in many parts of the world including India. The study is undertaken to study prevalence of dengue and its co-relation with various pathological parameters. 592 clinically suspected cases of dengue fever from November 2015 to July 2018 were included in the study. Blood samples for dengue serology, serum transaminases and platelet count (PC) were drawn in plain and EDTA test tubes. Dengue serology was performed by IgM MacElisa and NSI Antigen ELISA depending upon the duration of onset of fever. Platelet count was carried out on fully automated three part cell counter and serum transaminases study done on semi automated biochemistry analyser. Out of 592, 319 serum samples were tested for dengue NS1 ELISA and 54 samples were positive. 273 samples were tested for dengue IgM ELISA and 31 samples were positive. So prevalence rate of dengue was 14.36%. Majority of positive cases were males, having sex ratio of 1.93:1. Among dengue positive cases, 62.35% cases were found in 15-44 age group years. Varying degree of thrombocytopenia was seen in 87.05% positive cases. Serum transaminases level with normal acceptable range was noticed in 75.93% of dengue NS1 positives cases compare to elevate level in 77.42% of dengue IgM positive cases. The study draws attention toward the male, young adult age group. The overall significant increase in dengue IgM and dengue NS1 seropositivity among suspected cases in last few years indicates an increase in dengue virus activity. This study results indicate that dengue infection is not going to wane away but is going to stay and will play havoc if immediate control measures are not taken. The need of the hour is long-term vector control strategy; so that the outbreaks can be prevented.
Authors and Affiliations
Dr. Hema S Patel, Dr. Gaurav B Modi
Keywords
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