Prevalence of Extended-Spectrum β-Lactamases producing Klebsiella pneumoniae isolates in a tertiary care hospital in South India

Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 7

Abstract

Background: Growing antimicrobial resistance is of great concern in modern antibiotic era. Infections caused by multidrug resistant organisms like Klebsiella pneumoniae are among the leading causes of sepsis and infection related deaths. Aim: This study was done to determine the prevalence of ESBL producing Klebsiella in the various clinical specimens by phenotypic methods. Material and Methods: A prospective laboratory based study was done to determine phenotypically detect the presence of Extended Spectrum β-lactamases (ESBL’s) in samples received over a period of two years. A total of 7644 gram negative bacterial isolates were recovered from a total of 16526 clinical specimens received in the microbiology laboratory, over the two year period. Among the 2497 isolates of Klebsiella, 1157 isolates were ESBL positive (46%). Conclusion: Drug resistant Klebsiella producing ESBL are hard to treat, and infections caused by them can lead to fatal outcome. Effective antibiotic policy and rational use must be strongly and promptly implemented in all healthcare setups

Authors and Affiliations

Dr Shefali Gupta

Keywords

Related Articles

Clinico-Pathological Correlation of Thyroid Swellings

Aims and Objectives: To elucidate the clinical presentation of thyroid swelling and to assess the Clinico – Pathological correlation of thyroid swellings. Materials and Methods: A prospective observational study was cond...

Tissue Engineering: Emerging Concept in Oral Maxillofacial Reconstruction

Tissue engineering or tissue regeneration is a multidisciplinary field with the perspective to replace tissue loss as a result of the traumatic defect, oncosurgery, or organ damage.(1) As an alternative to current surgic...

Neuropsychiatric Manifestation in HIV/AIDS

Aim: To study the neuropsychiatric manifestations in patients with HIV / AIDS. Design: Cross – sectional study Methods: 50 male & female HIV positive / AIDS patients in the age range of 18-60yrs of age without any past p...

Developing the Integrated Health Service and Promotions Post for Non - Communicable Disease in Improving Cadres’ Skill, Knowledge, and Attitude of Community

Background: The existence of an integrated health service and promotions post called Posbindu for Non - Communicable Disease in Indonesia has been since 2005. But not all Posbindu achievement is not in line with the expe...

Oxidative Stress Markers and Its Correlation with Aminotransferases in Hepatic Manifestation of Dengue Virus Infection

Objective: To study the correlation between oxidative stress markers and Aminotransferases in patients of dengue fever with hepatic manifestations. Background: Manifestation of viral infection may be contributed by the a...

Download PDF file
  • EP ID EP517214
  • DOI -
  • Views 69
  • Downloads 0

How To Cite

Dr Shefali Gupta (2018). Prevalence of Extended-Spectrum β-Lactamases producing Klebsiella pneumoniae isolates in a tertiary care hospital in South India. Journal of Medical Science And clinical Research, 6(7), 772-776. https://europub.co.uk/articles/-A-517214