Prevalence of Extended-Spectrum β-Lactamases producing Klebsiella pneumoniae isolates in a tertiary care hospital in South India
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 7
Abstract
Background: Growing antimicrobial resistance is of great concern in modern antibiotic era. Infections caused by multidrug resistant organisms like Klebsiella pneumoniae are among the leading causes of sepsis and infection related deaths. Aim: This study was done to determine the prevalence of ESBL producing Klebsiella in the various clinical specimens by phenotypic methods. Material and Methods: A prospective laboratory based study was done to determine phenotypically detect the presence of Extended Spectrum β-lactamases (ESBL’s) in samples received over a period of two years. A total of 7644 gram negative bacterial isolates were recovered from a total of 16526 clinical specimens received in the microbiology laboratory, over the two year period. Among the 2497 isolates of Klebsiella, 1157 isolates were ESBL positive (46%). Conclusion: Drug resistant Klebsiella producing ESBL are hard to treat, and infections caused by them can lead to fatal outcome. Effective antibiotic policy and rational use must be strongly and promptly implemented in all healthcare setups
Authors and Affiliations
Dr Shefali Gupta
Keywords
Related Articles
- EP ID EP517214
- DOI -
- Views 67
- Downloads 0
Open Versus Retroperitoneal Laparoscopic Ureterolithotomy: A Propective Study from a Rural Center
Introduction- Laparoscopic ureterolithotomy has emerged as an important tool in management of ureteric calculi however open ureterolithotmy still being practiced. Aim- To compare the results of laparoscopic versus open u...
Study of Mucocutaneous Involvement in HIV in a Tertiary Care Centre
Background: Cutaneous manifestations are common among HIV infected persons. Certain characteristic skin changes can help clinicians to recognize previously undiagnosed HIV infection. Aims and Objectives: To determine the...
Assessment of Thyroid Functions in Critically Ill Patients
Background: The thyroid function tests triiodothyronine, thyroxine and thyrotropin are abnormal in critical illness. The pattern of abnormality depends on the severity of disease and thyroidal hormones can help in progno...
Urinary Cystatin C as an Early Biomarker of Acute Kidney Injury in Critically ill Patient
Introduction: Acute kidney injury is associated with high mortality in critically ill patients. We usually measure serum creatinine to detect AKI, but it is a poor predictor of accuracy particularly in the early stages o...
Concomitant Esotropias- An Analytical Study
Purpose: To report the incidence of various clinical types, predisposing factors and associations of concomitant esotropias. Design: Prospective randomized population based study. Materials & Methodology: 100 patients wh...