PREVALENCE OF FLUOROSCOPIC CALCIUM IN PATIENTS WITH CORONARY ARTERY DISEASE AND ITS ASSOCIATION WITH VARIOUS RISK FACTORS
Journal Title: IJSR-International Journal Of Scientific Research - Year 2018, Vol 7, Issue 2
Abstract
Background: Coronary artery calcification (CAC) is a predictor of coronary artery disease (CAD) and closely related to the predictor of future cardiac events. Objective: To assess the prevalence of fluoroscopic calcium in patients with CAD and to determine its association with various coronary risk factors. Methods: The CAC measurement was conducted by visual identification during fluoroscopy. The study subjects were allocated into two group, according to the presence (+) or absence (-) of CAC. The Syntax score was calculated from the results of coronary angiography. Results: Out of 846 patients, 236 patients represented CAC(+). The mean±SD age of the total study patients was 61±5.8 years with a male preponderance of 415(71.2%). Systolic/diastolic blood pressure was 132±24/80±13mm Hg in CAC(+) patients. The present study finding elucidated that diabetes (Adjusted Odds Ratio [OR], 8.52, 95% confidence interval [CI], 6.2-12.5, P=0.02), hypertension (OR, 5.52, 95% CI, 3.2- 8.4, P=0.03), and Syntax score (OR, 12.40, 95% CI, 8.82-16.56; P=0.001) were more prevalent in CAC(+) group compared to CAC(-) group. Those patients with family history of CAD had significant CAC as compared to those without CAD family history (OR, 3.32, 95% CI, 2.8-5.3, P=0.04). Conclusion: The prevalence of CAD among diabetic and hypertensive patients undergoing coronary calcification is significant. Therefore, screening of CAC should be considered in such patients for the better identify of their risk of cardiovascular complications.
Authors and Affiliations
Kurukkanparambil S. Mohanan, Vijo George, Poornima K. Nanu
Keywords
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