Prevalence of gamma-glutamyltransferase and mean corpuscular volume laboratory markers in alcohol dependent patients
Journal Title: Alkoholizm i Narkomania - Year 2018, Vol 31, Issue 4
Abstract
Introduction DSM-5/APA indicates three sensitive laboratory markers of heavy drinking useful in the diagnosis of alcohol use disorders: mean corpuscular volume (MCV), gamma-glutamyltransferase (GGT) and carbohydrate-deficient transferrin (CDT). The study aim was to identify the proportion of the occurrence of the abnormal values of the readily available laboratory tests for MCV and GGT among the patients with alcohol dependence at the time of their admission for treatment. Material and methods There were 543 patients included in the study, with average age 45 (SD ± 12.3) years, 72% were males. Clinical diagnosis of alcohol dependence was assessed according ICD-10/WHO criteria. Results Increased values of MCV were detected in 44% of patients and GGT in 50%. At least one marker was increased in 64% of the patients. Conclusions Significant proportion of patients with alcohol dependence had normal values of MCV and GGT at the time of treatment admission. The findings indicate the important, but only supportive role of these laboratory markers in the alcohol use disorders assessment. Clinical assessment of patient’s condition according to valid diagnostic criteria has a crucial role in the diagnosis of alcohol dependence.
Authors and Affiliations
Lubomir Okruhlica, Zuzana Kamendy
Keywords
Related Articles
- EP ID EP509464
- DOI 10.5114/ain.2018.83750
- Views 83
- Downloads 0
Authoritarianism, attitudes toward harm reduction and the stigmatisation of people who use drugs
Introduction While much research has been conducted in the past two decades on the stigma of mental health, relatively little has been published on the stigma of drug use and addiction, or attitudes toward harm reduction...
Odczucie głodu alkoholowego w ocenie osób uzależnionych
Wprowadzenie Celem badań było określenie poziomu intensywności odczuwania głodu alkoholowego przez osoby uzależnione oraz różnic w jego występowaniu ze względu na płeć i wiek. Przeanalizowano również związki pomiędzy od...
The ESPAD project: history and assumptions. Introduction to series of papers from the ESPAD study 1995-2015. Poland against the background of Europe
The ESPAD (European School Survey Project on Alcohol and Other Drugs) study is carried out in a changing number of European countries every four years since 1995. In 1995, 22 countries participated in the survey and 34 i...
Teratogenic action of alcohol
Maternal alcohol drinking might be deleterious to the developing fetus. At present, studies concentrate more on the teratogenicity of alcohol per se than conditions associated with chronic alcoholism. Severity and nature...
Drinking under control programmes: perception of alcohol-related harm reduction measures in Poland. Results of qualitative study among outpatient alcohol treatment providers
Introduction: Harm reduction programmes for drug addicts are well documented and accepted by practitioners, whereas harm reduction programmes for alcohol addicts are under researched and encounter resistance. The article...