Prevalence of Group A Streptococcal Carriage Rate in Asymptomatic Children
Journal Title: National Journal of Laboratory Medicine - Year 2019, Vol 8, Issue 2
Abstract
ABSTRACT Introduction: Streptococcus pyogenes is a Gram positive cocci causing respiratory infections commonly in children. Throat carriers are children in whom the organism is isolated from throat swab specimens in the absence of symptoms. This study was conducted in the institution to screen children for the detection of pharyngeal carriage rate of Group A Streptococci (GAS) and to compare the efficiency of two different methods for the diagnosis of S.pyogenes. Aim: To study the prevalence of Group A Streptococcal carriage rate in throat swabs of children. Materials and Methods: This is a prospective study conducted from March 2018-June 2018 (4 months) on 100 asymptomatic children attending the Pedodontics OPD of a self financing Dental College and Hospital. Two throat swabs were collected for bacteriological culture and rapid strip testing for detection of S.pyogenes was done. Results: Out of 100, 64 children (64%) were found to be in the age group between 6-10 years. Fourteen (14%) of the children showed growth of Streptococcus pyogenes on culture and 18 of them (18%) were positive by the rapid test method. Rapid test strips were found to be 85.7% sensitive and 93% specific for the detection of GAS carriage. Conclusion: Determination of carrier rate is important though there are no recommended guidelines for aggressive treatment of carriers. Throat culture remains the gold standard investigation for isolation of Streptococcus pyogenes, but Rapid antigen detection kits have proved to be valuable as a point of care test for rapid diagnosis.
Authors and Affiliations
Krishnarao Arthi, S Geetha Banu
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