Prevalence of group B Streptococcal colonization among pregnant women and neonates in a tertiary hospital in India
Journal Title: UNKNOWN - Year 2017, Vol 18, Issue 4
Abstract
Objective To estimate the prevalence of group B Streptococcus (GBS) carriage among pregnant women attending the antenatal clinic, and the colonization rates among newborn born to colonized mothers. Materials and Methods Women attending the antenatal clinic between 35-37 weeks were screened using rectal and lower vaginal swab. Swabs were initially plated on sheep blood agar and LIM broth. The LIM broth was subcultured after 24 hours onto blood agar and CHROMagar StrepB plates with all plates checked for growth at 24 and 48 hours. All babies born to mothers in the study had surface swabs taken to estimate the vertical transmission rate. Results Between September 2012 and March 2013, 305 consecutive mothers were screened. Of these, eight mothers were GBS positive in 5% blood agar (2.6%) and 23 mothers showed GBS positivity in enriched media (7.6%). Sixteen of 238 babies (6.7%) were colonized. Conclusion Though lower than rates from most countries, 7.6% of mothers attending an antenatal clinic in south India were colonized with GBS. Use of enrichment media markedly increased the detection rate. Approximately two-thirds of newborn born to colonized mothers were also colonized. There were no instances of invasive GBS disease, indirectly proving the efficacy of intrapartum prophylaxis in preventing neonatal GBS disease.
Authors and Affiliations
Sridhar Santhanam, Ruby Jose, Rani Diana Sahni, Niranjan Thomas, Manisha Madhai Beck
Keywords
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- EP ID EP380043
- DOI 10.4274/jtgga.2017.0032
- Views 55
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