Prevalence of hemoglobin abnormalities in kindergartens of the city of Parakou (Benin) in 2013
Journal Title: Journal of Research in Biology - Year 2015, Vol 5, Issue 5
Abstract
Introduction: The hemoglobinopathy is a real public health problem in the world The aim of this study to épister of children with abnormalities of hemoglobin in schools, especially kindergartens in the city of Parakou Republic of Benin. Methods: This is a descriptive cross-sectional study, conducted in kindergartens in the city of Parakou in Benin republic and having concerned 690 children aged 2 ½ to 5 years. The hemoglobin electrophoresis was done using alkaline pH hydragel and the quantification of haemoglobin fractions were performed with Hyrys densitometer; in some cases the medium is reduced for precipitation test. Results: Five types of Hb were identified: A, S, M, C and K probably Woolwich. Qualitative hemoglobinopathy was found in 31.45% of the study population. The Hb-S was the most frequent (16.52%) followed by hemoglobin C (15.65%). Hereditary persistence of hemoglobin F was associated with phenotypes AA, AC and SS in 1.16% of cases. The hemoglobinopathies were found in all the major ethnic groups in Parakou with a clear predominance among "Lokpa" (53.3%) and "Adja" (37.5%). Conclusion: The hemoglobinopathy is a real public health problem in Parakou, it is necessary to establish or to legislate for mandatory testing for hemoglobinopathies at birth.
Authors and Affiliations
Marius Dakpo, Moutawakilou Gomina, Joseph Agossou, Didier Adedemy, Alphonse Noudamadjo, Simon Ayelèroun Akpona
Keywords
Related Articles
- EP ID EP567615
- DOI -
- Views 65
- Downloads 0
Floristic diversity along an altitudinal gradient of Mannavan Shola forest in Southern Western Ghats of Kerala
The present study was carried to assess the variability in the species diversity using appropriate quantities and statistical analysis along the altitudinal gradients in the Mannavan shola forest in Kerala. The analysis...
Antiulcer activity of Property fruit extract of the Cucumis trigonus L. In albino rats
The effect of alcoholic fruit extract of Cucumis trigonus L. (Family: Cucurbitaceae) was evaluated for the anti-ulcerogenic activity with aspirin induced ulceration in albino rats and various biochemical parameters viz.,...
Plasma protein markers for estimating the population genetic structure of Amazon turtle (Podocnemis expansa Schweigger, 1812)
This study aims to test the potential of allelic frequency distributions of plasma proteins analysed by starch gel electrophoresis for identifying Amazon turtle (Podocnemis expansa Schweigger, 1812) stocks. Three protein...
Enumeration of medicinal plants along kanher and mahadare reservoir from Satara District, Maharashtra, India
The present study deals with traditional knowledge of medicinal plants recorded along the two reservoirs. Local people are using these plants for treatment of various diseases to cure it. The study records 56 different m...
Controlling asthma and related allergies - alternative options
Asthma is a medical condition that causes narrowing of small airways in the lungs. Asthma is a chronic inflammation of lung passages, involving eosinophils, mast cells, T-cells, neutrophils, macrophages. Typically, asthm...