PREVALENCE OF HEPATITIS-B AMONG THE VOLUNTARY BLOOD DONORS AT THE DEPARTMENT OF IMMUNOHAEMATOLOGY AND BLOOD TRANSFUSION IN A TERTIARY CARE HOSPITAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 4
Abstract
BACKGROUND Hepatitis B virus infection is a global health problem. Approximately, 30% of world’s population have serological evidence of either current or past infection with hepatitis B virus. (1) HBV causes a spectrum of diseases from self-limited hepatitis to acute fulminant and chronic hepatitis, which may result in sequelae like liver cirrhosis and hepatocellular carcinoma. The aim of this study is to study the seroprevalence of HbsAg among the voluntary blood donors. MATERIALS AND METHODS It is a retrospective descriptive study. 5 mL blood sample was collected from the blood bag of each donor. 2 mL blood was kept for testing Hepatitis B. ELISA kit was used for the screening of the donors. All reactive samples were tested again using the same ELISA kit. Samples showing repeat test reactivity on both methods were considered positive and were included for calculation of seroprevalence. RESULTS Total number of donors were 24,291. Out of them, only 349 were seropositive (prevalence of 1.5%, i.e. low prevalence). CONCLUSION Vellore region is one of the few regions from India where seroprevalence of HBsAg is low
Authors and Affiliations
Radhika Arumugam Rangaraj, Gayathri Purushothaman
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