Prevalence of Hepatitis B and Hepatitis C Infections in HIV Infected Patients Attending a Tertiary Care Hospital in North-East India
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 10, Issue 4
Abstract
Aims: To study the co infection of Hepatitis B (HBV) and/or Hepatitis C virus (HCV) in Human Immunodeficiency Virus (HIV) infected patients attending tertiary care teaching hospital in North East India. Study Design: This study was a cross sectional study. Place and Duration of the Study: Department of Microbiology, Guwahati Medical College & Hospital, Guwahati, Assam, India for a period of one year (August 2010- July 2011). Methodology: Serum samples of 180 HIV positive patients were collected randomly who gave consent to participate in the study and were tested for hepatitis B surface antigen (HBsAg) and anti-HCV antibodies by enzyme linked immunosorbent assay (ELISA) method. The retrospective demographic data of the subjects were collected. Results: Out of 180 HIV positive patients (126 males and 54 females), 22 (12.2%) cases were HBsAg positive and 8 (4.4%) were anti-HCV positive. Triple infection with HBV, HCV and HIV was not found in any patient. The commonest mode of transmission for HIV alone (113/180; 75.3%) and HIV-HBV co infection (18/22; 81.8%) was sexual route, and for HIV-HCV co infected patients, Intravenous Drug Use (IDU) was the commonest route of transmission (4/8; 50%). Concomitant infection of HIV and HBV was found to be significantly more in the symptomatic group (59.1%) compared to asymptomatic group (4.5%) (P value < 0.001). CD4+ T-lymphocyte count less than 200/μl was seen in 11 of 30 co-infected cases (36.7%). Conclusion: Co infection with HBV and HCV is a common problem in HIV infected patients in India. Hence, all HIV patients need to be routinely screened for markers such as HbsAg for hepatitis B and Anti HCV for HCV infection so as to take early treatment initiative to prevent the morbidities.
Authors and Affiliations
Sanjib Gogoi, N. K. Hazarika, Syed Tanwir Alam, Jashbeer S. Roy, Dina Raja
Keywords
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- EP ID EP348176
- DOI 10.9734/BJMMR/2015/19155
- Views 63
- Downloads 0
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