Prevalence of HIV, HBV, and HCV Markers in Multi-transfused Patients
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 7
Abstract
Background: Transfusion-transmitted infections (TTIs) are a major challenge to the transfusion services all over the world. The problem of TTIs is directly proportional to the prevalence of the infections in the blood donor community. Proper vigilance and quality control are needed to prevent this problem. Materials and Methods: The study was conducted in the Department of Pathology, Pt J.N.M. Medical College and DR. B.R.A.M. Hospital, Raipur C.G., from January 2012 to August 2013 among the patient who are admitted for blood transfusion and are having a history of multiple blood transfusions. Serological detection of HIV-1 and 2, HBV, and HCV was done by third-generation enzyme-linked immunosorbent assay method. Results: The study included 100 multi-transfused patients (MTPs), 56 (56%) were of sickle cell anemia, 26 (26%) were of thalassemia, 14 (14%) were of leukemia, and 4 (4%) were of aplastic anemia. 64 were males and 36 were females, with M/F ratio of 1.77:1. Majority were in age group of 6-10 years (36%). Out of 100 MTPs, 13 patients (13%) were found seropositive for viral markers. Out of 13 seropositive patients, 3 (3%) were seropositive for HIV 1 and 2, 10 (10%) were seropositive for HBV, and none of the patient was seropositive for HCV. Conclusion: The overall prevalence of anti-HIV, HBsAg, and anti-HCV in MTPs was found to be 3%, 10%, and 0%, respectively. Possible risk factor for seropositivity of MTPs may be blood transfusion as elicited by taking a history of the patient. Thus, the results of this study “raise an alarm to the existence of a significant risk” of TTIs in our society.
Authors and Affiliations
Vijay Kapse, Chandrakala Joshi, Ashok Verma
Keywords
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