Prevalence of Human Papilloma Virus infection in nonsmoker patients with Squamous Cell carcinoma of tongue by polymerase Chain Reaction in south of Iran, Shiraz
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 4
Abstract
Abstract: Human papilloma virus(HPV) as one of the important causal agent of gynecological cancers appears to play an important role in cancer of oral cavity and oropharynx. This study was aimed to evaluate the relationship between presence of HPV and squamous cell carcinoma(SCC) of tongue in non-smokers patients in south of Iran. In this case control study, pathologic specimen of 35 nonsmoker patients with histological diagnosis of tongue SCC, compared with 30 specimen of patient with tongue lesion other than intraepithelial neoplasms. Polymerase chain reaction (PCR) was used to detect HPV16 and 18 genome in both groups.(10) of (35) in case group and (1) of (30) in control group, 28.5% versus3.3% showed presence of HPV genome by use of PCR. chi-square test used for statistical analysis of data (p value=0.007). Although this study support the strong association between HPV infection and tongue SCC in non-smokers, but because of rarity of tongue SCC, planning for more advanced studies are suggested to prove this association. Keywords: Human Papilloma Virus, Squamous Cell Carcinoma, Polymerase chain reaction, Tongue cancer.
Authors and Affiliations
Fatemeh khajeh, Ahmad Monabati, Perikala Vijinada Kumar
Keywords
Related Articles
- EP ID EP372797
- DOI -
- Views 57
- Downloads 0
Phototherapy Induced Hypocalcemia in Neonates
The objective is to study the effect of phototherapy on serum calcium in neonates. A Cross sectional study was performed in a Tertiary care centre, Gandhi Medical College, Bhopal. Study group includes neonates with hyper...
A Retrospective Study of Tympanoplasty in Urban North Indian Pediatric Patients
Retrospective evaluation of medical records, of 41 pediatric patients, who underwent type I tympanoplasty, for isolated unilateral ear drum perforation, at the city charitable hospital, was done. Anatomical correction of...
Assessing the knowledge regarding organ donation in the B.COM students of H.L Commerce College
Abstract: Views of organ donation are positive but still there is a wide gap between the numbers of registered donors compared to those awaiting organ donations on a global level.The objectives of this study are -1.To as...
Prevalence of Endometrial Lesions in a Southern Tertiary Hospital in Nigeria (Jan. 2005-Dec. 2012)
The aim and objective of the study was to determine the pattern of endometrial lesions (endometrial hyperplasia and endometrial carcinoma). A cross sectional study of results of 123 recorded diagnosed reports of patients...
Prevalence and Determinants of Neonatal Morbidity in a Rural Area of Dibrugarh District, Assam
Abstract: Newborn health is a foundation of child health and adult health. If proper care is not given to the mother right from conception till the neonatal period, the newborn suffers from various morbidities. The socio...