Prevalence of Hypothyroidism in Cholelithiasis Patients in Bikaner, Rajasthan (India)
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 3
Abstract
Background: For decades, there has been discussion whether thyroid disorders could cause gallstone disease. Gallstone formation is a complex process involving various mechanisms affecting the flow of bile and bile content. Hypothyroid patients are found to have biliary stasis because of slowed emptying of bile from the biliary tract into the duodenum. This is attributed to the decreased pro-relaxing action of thyroxine on sphincter of Oddi in hypothyroid individuals. The hallmark laboratory investigation to detect hypothyroidism and also a sensitive indicator for diagnosing early thyroid dysfunction is serum TSH level. Serum TSH level is the most accurate indicator of thyroid function. This study attempts to know the prevalence of hypothyroidism in cholelithiasis. Material and Methods: A cross-sectional study was done between May 2015 to October 2015. 50 patients diagnosed as cholelithiasis in Department of General Surgery, at P.B.M. Hospital, were included in the study. Full history, clinical examination, ultrasound abdomen and laboratory blood test for free T3, free T4 and TSH were done for every patient. Data was analysed statistically using SPSS version 19.0. Results: Out of 50 patients of cholelithiasis, 29 (58%) were females and 21 (42%) were males. Thyroid disorder in form of hypothyroidism was found in 19 (38%) patients. In that, 11 (22%) patients presented with subclinical hypothyroidism and 8 (16%) patients with clinical hypothyroidism. Conclusion: There is an increase in prevalence of hypothyroidism in cholelithiasis in this study. The prevalence was more among >40 years age group. This increase in prevalence could have an effect on the diagnostic and therapeutic workup of cholelithiasis patients.
Authors and Affiliations
Kedar Nath, Ashok Kumar, Jitendra Acharya
Keywords
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- EP ID EP547792
- DOI 10.21276/ijmrp.2017.3.3.014
- Views 82
- Downloads 0
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