Prevalence of Hypothyroidism in Prgnancy And Pregnancy Outcome
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 2
Abstract
The second most common endocrinological disorder in pregnancy is thyroid dysfunction. The most common cause of hypothyroidism is primary abnormality in thyroid. Thyroid hormone is essential for the normal development of the placenta. There is evidence that preeclampsia, placental abruption and preterm labor are all causatively linked to faulty early placentation. Thyroid hormone is important for normal neuronal migration, synaptic transmission and myelination during the early stages of neurodevelopment and hence healthy development of foetus. Aim Of The Study: To study the prevalence of hypothyroidism in pregnancy and the pregnancy outcome in those pregnancies. This study involves screening 1000 consenting eligible women during first trimester. They will be subjected to TSH screening and if the values are deranged then they will undergo FT4. Based on the reports they will be classified as euthyroid, hypothyroid, subclinical hypothyroid and hyperthyroid. For the purpose of this study the patients who are hypothyroid and subclinical hypothyroid will be followed till the termination of pregnancy. All the patients will be treated based on the thyroid profile. Thyroid profile will be repeated every 4 weeks up to 20 weeks and at 32 weeks of gestation and doses titrated accordingly. The normal patients will serve as controls. In our study, there is an increase in the number of spontaneous abortion, GDM, Pre-eclampsia, oligohydramnios, preterm labor, IUGR and low birth weight in inadequately treated group. Hence early diagnosis and adequate treatment of maternal hypothyroidism in pregnancy is essential in decreasing the incidence of complications like abortion, pre eclampsia, IUGR, placental abruption, oligohydramnios and low birth weight which are associated with hypothyroidism.
Authors and Affiliations
Dr. Thenmozhi
Keywords
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- DOI 10.9790/0853-1602070516.
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