Prevalence of Latent Tuberculosis Infection in Type 2 Diabetic and NonDiabetic Individuals
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 6
Abstract
Objective: To study the prevalence of latent tuberculosis infection (LTBI) between Asian Indian type 2 diabetic and non-diabetic individuals. Methods: Participants with type 2 diabetes (n=98) and age and sex matched controls without diabetes (n=98) were recruited from Institute of Non Communicable diseases, Government Kilpauk medical College, Chennai. LTBI was defined as in duration of ≥10mm after Tuberculin Skin Test (TST) and with no abnormality in Chest X-ray based on WHO 2015 guidelines and Center for Disease control and prevention (CDC, USA) guideline. Type 2 Diabetes Mellitus (T2DM) was defined based on WHO criteria. Biochemical and anthropometric measurements were done using standardized procedures. Results: The 196 participants included 102 women (44.9%). Mean age was 41 ± 9 .4 years and mean body mass index (BMI), 26.32 ± 4 kg/m². The prevalence of LTBI among diabetic and non-diabetic individuals were 35.7% and 12.2 %, respectively (p ≤ 0.001). The mean Tuberculin skin test (TST) In duration values were significantly higher in diabetic, (7.18 ± 3.0 mm) compared to non-diabetic, participants (5.58 ± 3.05 mm, p= 0.002). Conclusion: Prevalence of Latent Tuberculosis Infection is higher among Asian Indian type 2 diabetic subjects compared to age and sex matched non-diabetic participants.
Authors and Affiliations
Kandasamy Venkatraju Rajalakshmi M. D
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