Prevalence of Latent Tuberculosis Infection in Type 2 Diabetic and NonDiabetic Individuals

Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 6

Abstract

Objective: To study the prevalence of latent tuberculosis infection (LTBI) between Asian Indian type 2 diabetic and non-diabetic individuals. Methods: Participants with type 2 diabetes (n=98) and age and sex matched controls without diabetes (n=98) were recruited from Institute of Non Communicable diseases, Government Kilpauk medical College, Chennai. LTBI was defined as in duration of ≥10mm after Tuberculin Skin Test (TST) and with no abnormality in Chest X-ray based on WHO 2015 guidelines and Center for Disease control and prevention (CDC, USA) guideline. Type 2 Diabetes Mellitus (T2DM) was defined based on WHO criteria. Biochemical and anthropometric measurements were done using standardized procedures. Results: The 196 participants included 102 women (44.9%). Mean age was 41 ± 9 .4 years and mean body mass index (BMI), 26.32 ± 4 kg/m². The prevalence of LTBI among diabetic and non-diabetic individuals were 35.7% and 12.2 %, respectively (p ≤ 0.001). The mean Tuberculin skin test (TST) In duration values were significantly higher in diabetic, (7.18 ± 3.0 mm) compared to non-diabetic, participants (5.58 ± 3.05 mm, p= 0.002). Conclusion: Prevalence of Latent Tuberculosis Infection is higher among Asian Indian type 2 diabetic subjects compared to age and sex matched non-diabetic participants.

Authors and Affiliations

Kandasamy Venkatraju Rajalakshmi M. D

Keywords

Related Articles

The influence of transport and irradiation on the longevity of male Aedes aegypti (Diptera: Culicidae)

Transport of sterile male mosquitoes from the location of irradiation to the release area possibly affects survival and mating competitiveness. The aim of the current research was to determine the influence of transporti...

Comparative Study of Soft Tissue Neoplasm with Reference to Cytology & Histopathology

Although tradition open incisional biopsy remains the diagnostic gold standard, FNAC has been identified as a useful diagnostic technique in the initial diagnosis of soft tissue neoplasm and is gaining importance because...

Study of Blood Pressure and Lipid Profile in Uncontrolled Diabetes Mellitus

Hypertension and Dyslipidemia are common accompaniments of Diabetes Mellitus and are major risk factors for cardiovascular diseases. This is a study of hypertension and lipid profile in 35 subjects with uncontrolled diab...

Effect of Glycemic Control on Radiographic Presntation of Pulmonary Tuberculosis in Type 2 Diabetes Mellitus

Introduction: Tuberculosis (TB) remains to be a major cause of morbidity and mortality throughout the world. The link of Diabetes (DM) and TB is more prominent in developing countries and the higher susceptibility of tub...

Septo-Optic Dysplasia: A Case Report

Septo-optic dysplasia also referred to as de Morsier syndrome and is a disorder of early brain development. Three characteristic features are under development (hypoplasia) of the optic nerve, abnormal formation of struc...

Download PDF file
  • EP ID EP521946
  • DOI -
  • Views 16
  • Downloads 0

How To Cite

Kandasamy Venkatraju Rajalakshmi M. D (2017). Prevalence of Latent Tuberculosis Infection in Type 2 Diabetic and NonDiabetic Individuals. Journal of Medical Science And clinical Research, 5(6), 23617-23623. https://europub.co.uk/articles/-A-521946