PREVALENCE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN HYPOTHYROIDISM IN A TERTIARY CARE HOSPITAL IN EASTERN INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 79
Abstract
BACKGROUND Thyroid hormones are involved in lipid metabolism, insulin resistance and regulation of bodyweight. There are inconclusive data regarding substantial involvement of hypothyroidism in non-alcoholic fatty liver disease (NAFLD). The aim of this study is to evaluate the prevalence of NAFLD in hypothyroidism. MATERIALS AND METHODS A descriptive study was conducted in the Department of General Medicine of SCB Medical College, Cuttack and consecutively 100 adult non-obese hypothyroid patients (50 treated and 50 untreated) were included in the study, and the patients were evaluated for NAFLD using ultrasonography. The results were compared with 100 age, sex and body mass index (BMI) matched euthyroid controls. RESULTS From 100 hypothyroid patients, 30 NAFLD patients were detected and 12 NAFLD patients were detected in controls (p=0.003). There was increased incidence of NAFLD in persons with high serum TSH value (≥4.1 mIU/ L) and low free T4 value (≤0.7 ng/dL). CONCLUSION Prevalence of NAFLD in non-obese hypothyroid patients is higher in comparison to non-obese euthyroid controls, and the incidence is also high in untreated hypothyroid patients in comparison to treated hypothyroid patients.
Authors and Affiliations
Rina Mohanty, Samarendra Nath Das, Aujjwalya Kumar Jena, Sarita Behera, Nirmal Chandra Sahu, Bijendra Mohanty, Sarada Priyadarshini Suna, Pravat Kumar Thatoi
Keywords
Related Articles
- EP ID EP268066
- DOI 10.14260/jemds/2017/1213
- Views 70
- Downloads 0
PREVALENCE OF NASH AMONG DIABETES
BACKGROUND NASH, or non-alcoholic steatohepatitis, was originally coined by Dr. Ludwig nearly 30 years ago to describe a distinctive entity considered by fatty changes with lobular hepatitis in the absence of a history o...
CORRELATION OF MEAN PLATELET VOLUME AND PLATELET DISTRIBUTION WIDTH IN RISK CATEGORIES OF DENGUE FEVER- A PILOT STUDY
BACKGROUND Incidence of dengue fever is on rise in India. We investigated the characteristics of Mean Platelet Volume (MPV) and platelet distribution width (PDW) in various risk categories of dengue fever. MATERIALS AND...
VITAMIN D3 LEVEL IN TYPE 2 DIABETES MELLITUS AND ITS CORRELATION WITH HbA1c LEVEL- A CROSS-SECTIONAL STUDY
BACKGROUND The role of vitamin D in type 2 diabetes is suggested by a seasonal variation in glycaemic control. It was reported in patients with type 2 diabetes being worse in winter, which might be due to hypovitaminosis...
REASONS FOR DELAYED UTILIZATION OF CATARACT SURGERY AMONG PATIENTS ATTENDING A TERTIARY REFERRAL CENTRE, MAHARASHTRA.
[b] BACKGROUND[/b]: Cataract is a major cause of vision impairment in many low-income settings. Cataract blindness is a disease which has severe economic repercussions and adversely affects the productivity of c...
A STUDY ON HYSTEROLAPAROSCOPY IN FEMALE INFERTILITY- A DIAGNOSTIC CUM THERAPEUTIC TOOL
BACKGROUND Infertility, according to WHO, is defined as “a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.” Inf...