Prevalence of Serum Antibodies to Torch Infection in Women with Bad Obstetrics History Attending Tertiary Care Hospital
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 8
Abstract
Introduction: The acute infections which are caused by Toxoplasma gondii, Rubella virus, Cytomegalovirus (CMV) and the Herpes Simplex Virus (HSV-2) during pregnancy are often associated with adverse foetal outcomes and reproductive failures. In the Indian context, the exact seroprevalence of these infections is not known due to unavailability of baseline data. Materials and methods: The present study was undertaken to determine the serological evidence of the acute TORCH infections in women who were in the first trimesters of their pregnancies in tertiary care hospital. 80 Sera were collected from the women with Bon and they were tested for the presence of specific IgM antibodies against the TORCH infections by ELISA. Results: The specific IgM antibodies were found to be positive in 18(18%)cases for toxoplasmosis, in 12(12%) cases for the Rubella virus, in 2 (2%) cases for CMV and in 2 samples (2%) for the HSV-2 infections. Conclusion: The study showed a high prevalence of the infections which were caused by the TORCH complex amongst pregnant women with bad obstetric histories. Therefore, all the antenatal cases should be routinely screened for the TORCH infections, for carrying out early interventions to prevent foetal loss.
Authors and Affiliations
Dr. Sai Spoorthi Gangili, Dr. Naresh Babu Sunkari
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