Prevalence of Silent Ischemic Heart Disease in Patients of Rheumatoid Arthritis
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 5, Issue 11
Abstract
Background: Almost half of the deaths in patients of rheumatoid arthritis (RA) are due to cardiovascular diseases. Many studies have shown that patients of RA are at increased risk of mortality and morbidity from ischemic heart disease (IHD). In half of the RA patients with confirmed IHD, the disease was clinically silent. Hence, early detection of the silent IHD is important to reduce the morbidity and mortality in patients of RA. Objectives: The objectives of this study were to determine the prevalence of silent IHD in RA patients, to identify the predictors of silent IHD in patients with RA and to study the correlation between silent IHD and RA disease activity. Methods: A total of 50 patients with a diagnosis of RA, attending the Medicine Outpatient Department and admitted in medicine wards of N.S.C.B. Medical College and Hospital, Jabalpur (M.P), were taken into the study determining the prevalence of silent IHD in RA. All patients fulfilled the 2010 ACR/EULAR classification criteria for RA. Results: Prevalence of silent IHD in RA patients in this study is 10%. There is significantly increased the incidence of silent IHD among patients with increased duration of RA, increased disease activity, and increased total cholesterol and erythrocyte sedimentation rate. Conclusions: There is a quite common prevalence of silent IHD in patients with RA. The predictors for silent IHD are prolonged disease duration, high disease activity, hypercholesterolemia, and presence of high activity markers.
Authors and Affiliations
Swapneel P Kadrekar, Silas Supragya Nelson
Keywords
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