Prevention and treatment of cognitive disturbances caused by combat trauma with the protection of energy supply of cells by reamberin
Journal Title: Медичні перспективи - Year 2018, Vol 23, Issue 1
Abstract
Objective: to investigate the state of cognitive functions in victims with combat trauma on the background of reamberin using. We studied 37 patients, injured simultaneously in different parts of the body during fighting, divided into treatment and control groups. The severity of the injury was determined by the ISS and EmTraS scales. The severity of the condition – according to generally accepted clinical and laboratory indicators, as well as by SAPS II scale. Cognitive functions were determined by the CFQ questionnaire (retrospectively the condition before the trauma and 3 months after was determined), MoCA (on day 2, when transferred from the intensive care unit and at discharge from the hospital). Results: It was established that by the severity of the injury and the incoming severity of the somatic state two groups did not differ statistically. The state of cognitive functions before wound in the wounded of both groups was not statistically different and was not beyond the norm. On the second day in the control group, the cognitive functions decreased to the level of dysfunction (82.7±5.0%), while in the main one they did not cross the control limit of 10% of the baseline level (89.0±2.2%). Further dynamics in the reamberin group confirmed its protective properties with respect to cognitive functions, but this effect was not prolonged after the end of therapy. Conclusion: The use of reamberin in the complex intensive care of severe combat trauma can prevent a significant decrease of cognitive functions in the early post-traumatic period, but this effect is of short aftereffect time, therefore, its prolonged usage is necessary for the stable recovery of cognitive functions.
Authors and Affiliations
A. A. Krishtafor
Keywords
Related Articles
- EP ID EP274703
- DOI 10.26641/2307-0404.2018.1.124919
- Views 67
- Downloads 0
Disorders of cardiac hemodynamic in attack period of bronchial asthma in children
By dopplerechocardiography method there was studied functional state of cardiac ventricles and character of hemodynamic disorders in 48 patients aged 5-17 years in attack period of moderately-severe and severe bronchial...
Морфометричний аналіз панцитокератин-негативних неопластичних ушкоджень лімфатичних вузлів шиї
Морфометрический анализ панцитокератин-негативных неопластических повреждений лимфатических узлов шеи. Пославская А.В., Шпонька И.С., Гриценко П.АК., Алексеенко А.А. Пациенты, имеющие диагноз рак с неизвестной первичной...
Peculiarities of rotavirus infection in children with different genotypes of the lactase gene
The aim was to study the peculiarities of rotavirus infection in children with various genotypes of the lactase gene LCT. Molecular genetic studies of LCT13910 gene polymorphism by polymerase chain reaction with electrop...
Statistical analysis of repair of complete removable dentures on the upper jaw for a three-year period of use
The aim of the study is a analyze the use of full dentures on the upper jaw and the number of repeated visits of patients who received treatment at the dental offices in the Dnepr city. Materials and methods: during 201...
Microbial landscape features in patients with generalized periodontitis at pre-clinical and radiological stage of its development
The paper presents the results of a comparative study of microbial landscape features in patients with generalized periodontitis at pre-clinical and radiological stage of its development in 42 patients. The purpose of th...