Prevention of Postdural Puncture Headache Following Accidental Dural Puncture: Two Cases Report and Mini Literature Review
Journal Title: Journal of Pharmaceutical Research International - Year 2016, Vol 12, Issue 2
Abstract
38 and 49 years old two women were admitted for total abdominal hysterectomy. Both patiens had no history of diabetes mellitus, hypertension, arrhytmia, myocardial ischemia, hyperkalemia, or local anaesthetic allergy. Also, there was no pathological finding in the preoperative laboratory evaluation. Initially, we planned combined spinal epidural anaesthesia (CSE) but because of accidental dural puncture (ADP), 15 mg hyperbaric bupivacaine 0.5% was injected into subarachnoid space through epidural needle for spinal anaesthesia. Later, the epidural needle was withdrawn into epidural space and a 20-gauge epidural catheter was easily placed into epidural space. At the end of the surgery, 10 ml of saline with 3 mg morphine was injected through epidural catheter and then continuous infusion of 10 ml.h-1 saline was admitted via epidural catheter during 24 hours postoperatively. A second injection of 3 mg morphine in 10 ml saline was repeated on the postoperative 24 h immediately before removal of the catheter. No patient need additional analgesic treatment and no adverse effect were observed in our two cases because of epidural morphine utilization. Following ADP, leaving the catheter in the epidural space and the administration of morphine injection with continuous saline infusion via epidural catheter may be an alternative to reduce the post dural puncture headache (PDPH).
Authors and Affiliations
Nurten Kayacan, Bilge Karslı, Celal Akgün
Keywords
Related Articles
- EP ID EP342112
- DOI 10.9734/BJPR/2016/25569
- Views 70
- Downloads 0
Antimicrobial Activity of Ethanolic Crude Extracts of Thespesia populnea Flowers
Aim: To analyze the antimicrobial activity of ethanolic crude extract of Thespesia populnea Flowers. Study Design: Antimicrobial activity of Thespesia populnea was carried out using disc diffusion method against crude ex...
Preparation and Evaluation of Matrix Tablet of Metronidazole Using Carnauba Wax
Aim: To formulate a sustained release tablet dosage form of metronidazole using carnauba wax as matrix former and binder. Methods: Batches of metronidazole tablets were formulated by using a combination of melt and wet...
Plants in Respiratory Disorders I- Anti-asthmatics, A Review
Aim of This Review: Respiratory disorders pose a big threat to life and constitute a major public health problem worldwide. This review is an attempt to bring together some of the common medicinal plants traditionally us...
Molecular Modeling of the Major Compounds of Sesquiterpenes Class in Copaiba Oil-resin
Aims: To study the Structure-Activity Relationship (SAR) and pharmacokinetic and toxicological properties (ADME/Tox) of the major compounds of sesquiterpenes class oil-resin extracted from the copaiba, using quantum chem...
Chemical Composition of the Stem Extract of Costus afer (Bush Cane) and Its Antimicrobial Activity
Aim: To determine the chemical composition of the stem extract of costus afer and its antimicrobial activity against some human and plant pathogens. Study Design: The s...