Primary Breast Lymphoma: A Study of 9 Cases
Journal Title: Journal of Cancer and Tumor International - Year 2016, Vol 4, Issue 3
Abstract
Aim: Non-Hodgkin's primary lymphoma of the breast is rare. These tumors represent 0.04 to 0.52% of malignant breast pathology, 2.2% of extranodal lymphoma and 0.4% of all non-Hodgkin’s lymphoma. Clinical and radiological aspects show no special characteristics. The aim of our study is to report the epidemiological, clinical and therapeutic features of patients with primary breast lymphoma. Patients and Methods: This is a retrospective study including 9 patients with primary non-Hodgkin's lymphoma of the breast treated at the institute Salah Azaiez from 2000 to 2013. This sample includes 1 case of follicular lymphoma, 1 case of large T-cell lymphoma and 7 cases of large B-cell lymphoma. Results: The average patient age was 50 years, ranging from 30 to 76 years. The sex ratio was 0.11 (1 man/8 women). The average consultation time was 3 months (5 days-8 months). The median follow-up period was 43 months (4-192 months).Six patients were older than 60 years; one had disseminated disease and was diagnosed with stage III Ann Arbor classification. All tumors were architecturally diffuse. The overall survival was 100% at one year and 75% at 3 years. Seven patients achieved complete remission after initial treatment, and one relapsed after 2 months. Among the 7 cases of large B cell lymphoma, two cases resulted from the transformation of follicular lymphoma. The average processing time was 17 months. Conclusion: Primary breast lymphoma is often diagnosed in the late stages of the disease. Treatment should be rapidly implemented. The 5-year survival of stage I of the Ann Arbor classification is higher than that for stage II.
Authors and Affiliations
Kmira Zahra, Olfa El Amine, Azza Gabsi, Aida Goucha, Jamel ben Hassouna, Khaled Rahal, Amor Gamoudi
Keywords
Related Articles
- EP ID EP243345
- DOI 10.9734/JCTI/2016/28910
- Views 110
- Downloads 0
Gallbladder Carcinoma in Ghana: Histopathological Examination of Cholecystectomy Specimen
Objective: The aim of the study was to find out the incidence of gallbladder carcinoma in cholecystectomy specimen and the histological types from Korle-Bu Teaching Hospital, Ghana. Methods: The study was a retrospective...
Do pathologists thoroughly Evaluate the Greater Omentum Following Gastrectomy for Malignancy: an Audit Based on Histopathology Reports
Introduction: Milky spots in greater omentum are primary sites for seeding of exfoliated cells from intra-abdominal malignancies. Surgery is the mainstay of treatment of gastric adenocarcinoma and the greater omentum is...
Macroscopic & Microscopic Molecular-associated Treatments of Monosodium Glutamate-induced Uterine Fibroid via Aqueous Extract of Ginger Rhizomes: A Study on Adult Female Wistar Rats
Background: Uterine fibroids are benign (non-cancerous) tumours that develop in the uterus [1,2]. They have been and still are a major reproductive threat to women of child-bearing age especially to those of the African...
Outcome and Predictive Factors of Radiation Therapy for Medulloblastoma: Mansoura Experience
Background: Medulloblastomas are the most common infratentorial malignant brain tumors with an incidence rate of 0.5 in 100.000 typically arising in childhood at age 5-9 years. Aim of Work: Exploring the epidemiological...
Level of Awareness on Breast Cancer and Practice of Breast Self-Examination among Market Women in Ido Community, Ido-Ekiti, Ekiti State, Nigeria
Aim: The study assessed the level of awareness on breast cancer and practice of breast self-examination among market women in Ido community, Ido-Ekiti, Ekiti State, Nigeria. Study Design: It made use of a descriptive res...