Primary Breast Lymphoma: A Study of 9 Cases
Journal Title: Journal of Cancer and Tumor International - Year 2016, Vol 4, Issue 3
Abstract
Aim: Non-Hodgkin's primary lymphoma of the breast is rare. These tumors represent 0.04 to 0.52% of malignant breast pathology, 2.2% of extranodal lymphoma and 0.4% of all non-Hodgkin’s lymphoma. Clinical and radiological aspects show no special characteristics. The aim of our study is to report the epidemiological, clinical and therapeutic features of patients with primary breast lymphoma. Patients and Methods: This is a retrospective study including 9 patients with primary non-Hodgkin's lymphoma of the breast treated at the institute Salah Azaiez from 2000 to 2013. This sample includes 1 case of follicular lymphoma, 1 case of large T-cell lymphoma and 7 cases of large B-cell lymphoma. Results: The average patient age was 50 years, ranging from 30 to 76 years. The sex ratio was 0.11 (1 man/8 women). The average consultation time was 3 months (5 days-8 months). The median follow-up period was 43 months (4-192 months).Six patients were older than 60 years; one had disseminated disease and was diagnosed with stage III Ann Arbor classification. All tumors were architecturally diffuse. The overall survival was 100% at one year and 75% at 3 years. Seven patients achieved complete remission after initial treatment, and one relapsed after 2 months. Among the 7 cases of large B cell lymphoma, two cases resulted from the transformation of follicular lymphoma. The average processing time was 17 months. Conclusion: Primary breast lymphoma is often diagnosed in the late stages of the disease. Treatment should be rapidly implemented. The 5-year survival of stage I of the Ann Arbor classification is higher than that for stage II.
Authors and Affiliations
Kmira Zahra, Olfa El Amine, Azza Gabsi, Aida Goucha, Jamel ben Hassouna, Khaled Rahal, Amor Gamoudi
Keywords
Related Articles
- EP ID EP243345
- DOI 10.9734/JCTI/2016/28910
- Views 105
- Downloads 0
Pathological Study of Colorectal Cancer in Missan Province
Aims: Colorectal cancer (CRC) is a major cause of morbidity and mortality in the worldwide and also ranks as the fifth-leading malignancy and death in Iraq. This study aimed to provide a present outlook of colorectal di...
Combined Intralipid-urotherapy for Patients with Cancer: A Creative Review
The article relates in general to intralipid and its use in cancer therapy. Specifically, it relates to the combined intralipid-urotherapy for treating cancer, and methods of such treatment. Cancer cells release various...
Ganglioneuroma Involving Deep Facial Structures - A Case Report
Ganglioneuroma is a rare peripheral neuroblastic tumor originating from the neural crest. It is a benign tumor involving posterior mediastinum and retroperitoneum. We present a case of 12-year-old boy who was diagnosed w...
Intracranial Hemangiopericytoma in a 15 Year-old Child: Neuroimaging Features and Management Therapy
Introduction: Intracranial hemangiopericytoma (HPR) is a highly vascular tumors which is exceptional in children. They may present management difficulties in some cases. Clinical Presentation: The authors report the case...
Nutritional Status of Lung Cancer Patients in Benghazi City of Libya
Lung cancer is one of the most common type of cancer in the world and Libya is no exception. Nutrition intervention is often needed for nutrition-related complications of cancer treatment, which include but are not limit...