Primary Cutaneous Hodgkin Lymphoma: A Rare Disease Variant and Review of the Literature
Journal Title: Journal of Case Reports and Studies - Year 2016, Vol 4, Issue 2
Abstract
A 49-year-old man presented with a 2-year history of an enlarging ulcerated plaque over the right forearm with an associated history of pruritus. Skin biopsy demonstrated an infiltrate of lymphocytes in the dermis and subcutis, together with atypical cells with large nuclei and prominent nucleoli resembling Reed-Sternberg cells. Immunohistochemical staining showed that the cells were positive for CD30 and CD15, but negative for LCA, CD20, CD3 & ALK1, consistent with classic Hodgkin Lymphoma. Computerized tomography, bone marrow biopsy and blood work-up revealed no systemic features, confirming a diagnosis of Primary Cutaneous Hodgkin lymphoma (PCHL). The patient received four cycles of ABVD (adriamycin, bleomycin, vinblastine and dacarbazine) with regression of the tumor but subsequently died due to pulmonary tuberculosis and pulmonary thromboembolism
Authors and Affiliations
Koch K
Keywords
Related Articles
- EP ID EP583280
- DOI 10.15744/2348-9820.4.204
- Views 96
- Downloads 0
Goldenhar Syndrome: A Perpetual Airway Challenge for the Anaesthesiologist
Patients with Goldenhar syndrome present as difficult airway to the anaesthesiologist due to various craniofacial anomalies like hemifacial microsomia, retrognathia and high arched palate. Also, these patients often unde...
Productive Cough and Bilateral Ptosis
We present a case report of a patient with Mounier-Kuhn syndrome. The clinical, radiological and endoscopic illustrations contribute to the awareness and recognizability of this rare and under-diagnosed pulmonary syndrom...
Resolution of Complete Atrioventricular Block in a Patient with Severe Hypothyroidism
Causes for syncope are multifaceted. Hormonal etiology, specifically hypothyroidism, is associated with cardiac arrhythmias [1]. Sinus bradycardia, low voltage, nonspecific T-wave changes and dissociative atrioventricula...
Antrochoanal Polyp Harboring Cholesterol Granuloma: A Case Study
Cholesterol granuloma (CG) is a foreign body reaction to the deposition and inadequate drainage of cholesterol crystals that are frequently found in association with chronic diseases. The clinical symptoms are non-specif...
Cardiac Permanent Pacing after a Correction of a Congenital Heart Defect
The incidence of complete heart block following Glenn’s shunt is not known. Complete heart block may occur immediately after surgery or early in the postoperative period and also may occur many months or years after surg...