Primary Hepatic B-Cell Lymphoma with Obstructive Jaundice: A Rare Case Presentation and Literature Review
Journal Title: Scholars Journal of Medical Case Reports - Year 2018, Vol 6, Issue 1
Abstract
Abstract: Primary hepatic lymphoma (PHL) is a rare form of non-Hodgkin's lymphoma, which usually presents with hepatomegaly, constitutional symptoms and signs of cholestatic jaundice without involvement of the bone marrow, spleen and lymph nodes at the early stage of the disease. PHL is often misdiagnosed as hepatitis, primary liver cancer or metastatic disease due to its non-specific clinical symptoms and perplexing laboratory results. This case is presenting a 66 year old female, who was primarily diagnosed with obstructive jaundice, which was a case of PHL based on full range of examinations. The patient presented with yellowish discoloration of the sclera, right upper quadrant pain, nausea, vomiting and fever. Physical examination revealed an enlarged liver with no evidence of generalized lymphadenopathy. Initial investigation with biochemical tests demonstrated a picture of obstructive jaundice, imaging studies revealed a large liver mass, which was confirmed by histopathology as PHL. The patient underwent chemotherapy by oncology service. Liver lymphomas might clinically present with obstructive jaundice masking other liver and biliary tree pathologies. Treatment of this pathology should be planned after thorough clinical and radiological examinations with the histological confirmation.
Authors and Affiliations
Dr. Talal S. Almukhlifi
Keywords
Related Articles
- EP ID EP481553
- DOI -
- Views 85
- Downloads 0
Impetigo Herpetiformis: A Rare Mode of Revelation of Hypocalcemia
Impetigo herpetiformis is a very rare and severe pustular dermatosis, which can be accompanied by fever, neuro-muscular disorders and digestive disorders; which can be life-threatening and requiring emergency management....
Unusual Presentation of Follicular Carcinoma Thyroid- A Rare Case Report
Follicular thyroid carcinoma rarely manifests itself as a distant metastatic lesion. We report a known case of goiter in 76-year-old woman with follicular thyroid carcinoma who initially presented with pain in left shoul...
Osteomyelitis of Femur Mimicking Ewings Sarcoma- A Case Report
Osteomyelitis in adult age group, i.e, after closure of epiphysis is usually non-hematogenous. Commonest causes of chronic osteomyelitis are usually compound fractures or secondary to surgical intervention. Suspicion of...
False positive pregnancy test in a patient presenting for colonoscopy
Gastrointestinal malignancies can rarely be associated with elevated βhCG which can result in positive pregnancy test. We present the case of a 37 year old female patient with intra-hepatic carcinoma and positive urine p...
Penetrating Trauma in Lower Chest Causing Gastric Fundal Perforation: A Rare Presentation
A 20 years old male presented to casualty with alleged history of penetrating injury to left lower chest with a metal rod. Vitals were stable on presentation. Radiological investigations were normal on presentation. Duri...