Primary Hepatic B-Cell Lymphoma with Obstructive Jaundice: A Rare Case Presentation and Literature Review
Journal Title: Scholars Journal of Medical Case Reports - Year 2018, Vol 6, Issue 1
Abstract
Abstract: Primary hepatic lymphoma (PHL) is a rare form of non-Hodgkin's lymphoma, which usually presents with hepatomegaly, constitutional symptoms and signs of cholestatic jaundice without involvement of the bone marrow, spleen and lymph nodes at the early stage of the disease. PHL is often misdiagnosed as hepatitis, primary liver cancer or metastatic disease due to its non-specific clinical symptoms and perplexing laboratory results. This case is presenting a 66 year old female, who was primarily diagnosed with obstructive jaundice, which was a case of PHL based on full range of examinations. The patient presented with yellowish discoloration of the sclera, right upper quadrant pain, nausea, vomiting and fever. Physical examination revealed an enlarged liver with no evidence of generalized lymphadenopathy. Initial investigation with biochemical tests demonstrated a picture of obstructive jaundice, imaging studies revealed a large liver mass, which was confirmed by histopathology as PHL. The patient underwent chemotherapy by oncology service. Liver lymphomas might clinically present with obstructive jaundice masking other liver and biliary tree pathologies. Treatment of this pathology should be planned after thorough clinical and radiological examinations with the histological confirmation.
Authors and Affiliations
Dr. Talal S. Almukhlifi
Keywords
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