PRIMARY MICROBIOLOGICAL SCREENING OF AMINO ACIDS AND THEIR MODIFIED VARIANTS
Journal Title: Annals of Mechnikov Institute - Year 2019, Vol 0, Issue 1
Abstract
The primary microbiological screening of 20 native amino acids and 52 modified variants thereof was carried out. A significant antimicrobial activity was established for synthetic derivatives against reference strains of gram-positive microorganisms (S. аureus АТСС 25923, B. subtilis ATCC6633), mild antimicrobial activity of new compounds towards gram-negative microorganisms (P. vulgaris ATCC 4636, E. coli АТСС 25922, P. aeruginosa ATCC 27853) and weak antimicrobial activity against Candida spp. fungi (C. albicans ATCC 885-653). The results of the primary microbiological screening of modified amino acids prove the relevance and potential of the further thorough study of the range and level of antimicrobial activity of the certain selected compounds with the aim to develop new antimicrobial agents.
Authors and Affiliations
T. P. , Osolоdchenko, I. D. , Andreieva, S. V. , Ponomarenko, A. N. , Komisarenko, O. M. , Koshoviy, N. P. , Zavada, I. S. Ryabova
Keywords
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- EP ID EP613663
- DOI 10.5281/zenodo.2639502
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