Primary Squamous Cell Carcinoma of Breast in a Young Female: An Institutional Experience with Review of Literature

Journal Title: Journal of Integrative Oncology - Year 2018, Vol 7, Issue 1

Abstract

Invasive or infiltrating ductal carcinoma is the most common type of breast cancer while primary squamous cell carcinoma of breast is extremely rare occurring in 0.04%-0.1% of all breast cancer cases known for aggressive behaviour and poor prognosis. We hereby report a case of primary squamous cell carcinoma of breast in a 31-yearold female who presented with a left breast lump of 2 months duration. Lumpectomy done at another non-oncology centre showed invasive ductal carcinoma with margin positivity for which she underwent modified radical mastectomy at our institute. Post-operative immune-histopathology revealed triple negative squamous cell carcinoma. Her metastatic work-up with whole-body positron emission tomography scan was negative. She was treated with adjuvant chemotherapy doxorubicin, cyclophosphamide and docetaxel followed by loco-regional radiotherapy to left chest wall which she tolerated well. No hormonal therapy was given in view of hormone receptor negativity. She is presently on follow-up for more than 6 months without any evidence of recurrence or distant metastasis. This case is being presented to highlight its extreme rarity, it’s occurrence in a young female, the diagnostic and therapeutic challenges it presented and the overall prognosis of this neoplasm.

Authors and Affiliations

Abhishek Purkayastha

Keywords

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  • EP ID EP348908
  • DOI 10.4172/2329-6771.1000204
  • Views 59
  • Downloads 0

How To Cite

Abhishek Purkayastha (2018). Primary Squamous Cell Carcinoma of Breast in a Young Female: An Institutional Experience with Review of Literature. Journal of Integrative Oncology, 7(1), 1-4. https://europub.co.uk/articles/-A-348908