Printable Self-Assembled Peptide Bio-Inks: Promising Future Applications in Nanomedicine
Journal Title: Archives of Nanomedicine: Open Access Journal - Year 2018, Vol 1, Issue 3
Abstract
In the current era of research and development, nanotechnology and additive manufacturing play a key role in the industry as well as in the healthcare applications. In order to explore medicinal applications, researchers focus on the design and synthesis of biocompatible nanoparticles and nanomaterials. Molecular self-assembly is a powerful approach for the fabrication of supramolecular functional materials. Self-assembly offers the integration of nanotechnology with the additive manufacturing for the fabrication of three dimensional (3D) printed objects. The cross-linked peptide hydrogels are gaining attention as potential bio-ink for the 3D bio-fabrication. The current article focuses on the scope of the printable peptide containing hydrogels as bio-ink in the fields of nanomedicine, drug delivery and tissue engineering. Design and the development of smart nanostructures that can diagnose and simultaneously cure the health problems are the main goals of the nanomedicine. Self-assembling bio-compatible functional nanomaterials and their therapeutic activity under biological environment are the key steps in order to develop effective nanomedicine. Among various approaches to fabricate nanostructures, self-assembly offers to fabricate supramolecular functional nanostructures from their individual building blocks. Self-assembly process involves through bottom-up approach to construct supramolecular nanostructures. The nanostructures including nanofibers, nanovesicles and micelles are formed through intra- and intermolecular covalent and non-covalent interactions. Self-assembles nanostructures formed by bioactive materials can be integrated with additive manufacturing for developing effective nanomedicine. The layer-by-layer bio-fabrication methods are introduced in healthcare due to their applications in 3D drug delivery systems, matured tissue cultures and in-vitro organ fabrications [1].
Authors and Affiliations
Apurba K Das, Rohit G Jadhav
Keywords
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- EP ID EP583422
- DOI 10.32474/ANOAJ.2018.01.000113
- Views 71
- Downloads 0
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